MIDTERMS

Question 1

SPOROTRICHOSIS CAUSATIVE AGENT

Answer 1

Sporothrix schenkii

Question 2

CHROMOBLASTOMYCOSIS CAUSATIVE AGENT

Answer 2

Phialophora verrucosa, Fonsecaea compacta

Question 3

MYCETOMA CAUSATIVE AGENT

Answer 3

Exophiala jeanselmei, Pseudoallescheria boydii

Question 4

RHINOSPORIDIOSIS CAUSATIVE AGENT

Answer 4

Rhinosporidium seeberi

Question 5

PHAEOHYPHOMYCOSIS CAUSATIVE AGENT

Answer 5

Wangiella (Fonsecaea) dermatitidis, Xylohypha bantiana

Question 6

Soil, vegetable debris, moist wood, wood pulp, & sphagnum moss used to mulch roses and other plants

Answer 6

SPOROTRICHOSIS

Question 7

Soil, wood and wood pulp, decaying vegetation

Answer 7

CHROMOBLASTOMYCOSIS

Question 8

Soil, manure, rotting wood

Answer 8

MYCETOMA

Question 9

Fish, aquatic insects

Answer 9

RHINOSPORIDIOSIS

Question 10

 humans and lower animals
 immunocompromised host

Answer 10

PHAEOHYPHOMYCOSIS

Question 11

chronic mycotic infection of the cutaneous or subcutaneous tissues or adjacent lymphatics

Answer 11

SPOROTRICHOSIS

Question 12

lesions
o nodule
o suppurative or ulcerative = serous, serosanguinous, or purulent fluid
o palpable
o painless

Answer 12

SPOROTRICHOSIS

Question 13

traumatic implantation

Answer 13

SPOROTRICHOSIS

Question 14

inhalation (very rare)

Answer 14

SPOROTRICHOSIS

Question 15

Secondary spread to articular surfaces, bone and muscle is infrequent

Answer 15

SPOROTRICHOSIS

Question 16

occasionally involve the CNS, lungs, or GUT

Answer 16

SPOROTRICHOSIS

Question 17

Other prominent features
o epithelial hyperplasia, fibrosis, and microabscess formation in the epidermis

Answer 17

CHROMOBLASTOMYCOSIS

Question 18

lesions
o nodule or papule
o tumorous
o cauliflower-like appearance (verrucoid & warty crusted nodules)
o painless, itchy

Answer 18

CHROMOBLASTOMYCOSIS

Question 19

chronic, suppurative infection of the subcutaneous tissue

Answer 19

MYCETOMA

Question 20

contiguous bone with clinical features fairly uniform regardless of the etiologic agent

Answer 20

MYCETOMA

Question 21

lesion:
o nodule
o small hard
o painless
o soften on the surface = viscous, purulent fluid containing grains
o Sinuses = serosanguinous fluid containing the granules

Answer 21

MYCETOMA

Question 22

GRAINS – hallmark

Answer 22

MYCETOMA

Question 23

Grains vary in size, colorant degree of hardness, depending on the etiologic species

Answer 23

MYCETOMA

Question 24

polypoid masses at nasal mucosa, conjunctiva, genitalia, and rectum only microorganism

Answer 24

RHINOSPORIDIOSIS

Question 25

classified in the class Mesomycetozoea and is pathogenic to mammals and birds

Answer 25

RHINOSPORIDIOSIS

Question 26

caused by a number of dematiaceous fungi where the tissue morphology of the causative organism is mycelial

Answer 26

PHAEOHYPHOMYCOSIS

Question 27

Invasion of the skin, lungs, and brain.

Answer 27

PHAEOHYPHOMYCOSIS

Question 28

''most common primary infection → lesion

Answer 28

Cutaneous sporotrichosis

Question 29

Primary infection → dissemination to lymphatic channels

Answer 29

Lymphocutaneous sporotrichosis

Question 30

follow the same indolent course as the primary lesion

Answer 30

Lymphocutaneous sporotrichosis

Question 31

No systemic symptoms

Answer 31

Lymphocutaneous sporotrichosis

Question 32

Primary infection → bone (joint) involvement: stiffness and pain in large joint (knee, elbow, ankle, or wrist)

Answer 32

Osteoarticular sporotrichosis

Question 33

 Relatively rare  inhalation of conidia  hematogenous route  Hemoptysis → death

Answer 33

Pulmonary sporotrichosis

Question 34

Clinical material:  tissue biopsy – best specimen

Question 35

Clinical material:  skin scrapings and(or) tissue biopsy

Question 36

Clinical material:  tissue biopsy of excised sinus

Question 37

Microscopic  Spherules filled with infected tissue  cannot be culture in vitro on artificial media

Question 38

Macroscopic  Young colonies appear as yeast like mucoid, shiny and black, while mature colonies appear as velvety but may become glabrous, olive gray to gray black with jet black reverse.

Answer 38

Wangiella dermatitidis

Question 39

Microscopic  Mature cells contains septate hyphae that are branching, greenish brown.

Answer 39

Wangiella dermatitidis

Question 40

Microscopic Phialides : conidiogenous cells that develop laterally or terminally form hyphae.

Answer 40

Wangiella dermatitidis

Question 41

Microscopic Conidia are small, ovoid to globose, unicellular with smooth walls.

Answer 41

Wangiella dermatitidis

Question 42

Macroscopic  Young colonies appear as olive gray to olive brown with a dark gray to black reverse.

Answer 42

Xylohypha bantiana

Question 43

Macroscopic  Mature colonies for obverse & reverse has dark gray or black color, velvety or cottony texture, typically flat.

Answer 43

Xylohypha bantiana

Question 44

Microscopic  Hyphae are septate and maybe branched, broad with brown pigment.

Answer 44

Xylohypha bantiana

Question 45

Microscopic Conidiation is cladosporium type.

Answer 45

Xylohypha bantiana

Question 46

Conidia : are long chains (35-40), produce acropetally (produced forth based toward the apex) in a tree like fashion.

Answer 46

Xylohypha bantiana