Midterm- Spina Bifida Flashcards
_ _ means divided spine, and refers to the non-fusion of vertebral arches. Term is used to refer to malformations involving the _ end of the _ _. AKA? (3)
Spina Bifida
Term is used to refer to malformations involving the caudal end of the neural tube.
AKA: myelodysplasia, myelomeningocele (MM), meningiomyelocele
Spina Bifida is caused by the failure of the neural tube to _ and subsequent _ _ development of the _ _ in that region. Associated with _ abnormalities and _ (incl. maternal alcohol intake, anticonvulsant intake, nutritional deficiencies- folic acid).
Failure of the neural tube to fuse and subsequent abnormal development of the embryonic tissue in that region. Associated with genetic abnormalities, and teratogens . . .
5 types myelodysplasia?
MOMMA
Spina Bifida with meningocele Spina Bifida Occulta (hidden) Spina Bifida with myelomeningocele Spina Bifida with myeloschisis Spina Bifida Aperta (visible)
What type of spina bifida is described: vertebral defect due to arches not fusing
Spina Bifida Occulta (hidden)
What type of spina Bifida is being described: dural space with or without spinal cord protruding
Spina Bifida Aperta (visible)
What type of spina Bifida is described: cyst-like protrusion containing meninges and CSF
Spina Bifida with Meningocele
What type of spina Bifida is described: cyst-like protrusion also containing spinal cord and/or nerve roots.
Spina Bifida with myelomeningocele
What type of spina Bifida is described: neural plate spinal cord stayed open and a flattened mass of nervous tissue formed.
Spina Bifida with myeloschisis
Myelomeningoceles usually cause a marked _ _ at and below the level of? Is?
Usually cause a marked neurological deficit at and below the level of the protruding sac
Is most of what is seen in the clinic
Hydrocephalus, Arnold- Chiari Type II malformation, spinal cord tethering, upper limb dis coordination, cranial nerve palsies, spasticites and seizures are all?
Examples of associated complications of Spina Bifida
Hydrocephalus is _ _ of _ in the _. -% require a _. 2 types?
Excessive accumulation of CSF in ventricles
80-90% require a shunt
2 types: ventriculoatrial shunt (VA) and ventriculoperitoneal shunt (VP)
What is described: Cerebellar hypoplasia and herniation of the hindbrain thru the foramen magnum, and cerebellar signs.
Arnold-Chiari Type II malformation
_ _ _ occurs from scarring of the neural placode or spinal cord to the overlying dura or skin with resultant traction on neural structures.
Spinal cord tethering
_ _ _ is characterized by halting deliberate movements. Frequently seen in children with Myelomeningocele who also have hydrocephalus. 3 possible causes?
Upper limb dyscoordination
MMC
- motor cortex or CS tract damage caused by hydrocephalus
- motor learning deficits resulting from use of UE’s for balance and support rather than manipulation and exploration
- Cerebellar ataxia associated with Arnold-Chiari Type II malformation
What are signs and symptoms of cranial nerve palsies? (5) Associated nerves? (3)
May have ocular motor palsies (CN 6), apnea, croupy, hoarse cry, and swallowing difficulties (CN 9, 10)