Midterm Review Flashcards

1
Q

What are vital signs?

A

Vital signs refer to the body’s essential physiological functions, including temperature, pulse, respiration rate, and blood pressure.

NOT considered vital signs: oxygen analysis

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2
Q

Compare etiology and epidemiology.

A

Etiology: Study of the cause of disease.

Epidemiology: Study of how often diseases occur in different groups of people and why.

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3
Q

Compare benign and malignant tumors

A

Benign tumors are slow-growing, encapsulated, and do not spread​.

Malignant tumors are aggressive, invade nearby tissues, and metastasize​.

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4
Q

What is the difference between undifferentiated and differentiated tumors?

A

Undifferentiated tumors: Cells do not resemble normal cells and tend to grow and spread quickly.

Differentiated tumors: Cells resemble normal cells and tend to grow and spread slowly.

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5
Q

What are the least and most radiosensitive tissues?

A

Least radiosensitive: Bone (not to be confused with bone marrow that is highly radiosensitive)

Most radiosensitive: Ocular lense muscle, nerve cells

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6
Q

Define neoplasm

A

A neoplasm is an abnormal growth of cells that persists after the stimulus is removed, classified as benign or malignant​.

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7
Q

What are anaplastic cells?

A

Anaplastic cells are undifferentiated, highly abnormal, and often associated with aggressive cancers​​.

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8
Q

What are the borders considered in breast cancer treatment?

A

Superior border: Inferior edge of the clavicle.

Inferior border: 1-2 cm below the inframammary fold.

Medial border: Midline of the chest.

Lateral border: Mid-axillary line or beyond, depending on lymph node involvement.

This ensures tumor and lymph node coverage while minimizing radiation exposure to nearby structures like the heart and lungs.

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9
Q

What types of mastectomies are performed in breast cancer treatment?

A

Total (Simple) Mastectomy: Removal of the entire breast without axillary lymph node dissection.

Modified Radical Mastectomy: Removal of the entire breast along with axillary lymph nodes.

Radical Mastectomy: Removal of the breast, chest wall muscles, and all axillary lymph nodes (rarely performed today).

Skin-Sparing Mastectomy: Removal of breast tissue while preserving most of the breast skin for reconstruction.

Nipple-Sparing Mastectomy: Removal of breast tissue while preserving the nipple and areola complex.

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10
Q

Question: What secondary cancers or conditions can arise from breast cancer treatment?

A

Radiation-induced secondary cancers: Such as sarcomas or cancers in nearby tissues like the lungs or esophagus.

Lymphedema: Swelling due to lymphatic system damage, often resulting from lymph node removal or radiation.

Cardiac complications: Particularly from radiation treatment near the left breast, increasing the risk of heart disease.

Bone weakening: Radiation or hormonal therapies can lead to osteoporosis or bone fractures.

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11
Q

Question: How is staging done for specific breast cancers?

A

Tumor (T): Evaluates the size and extent of the primary tumor.

Node (N): Assesses whether cancer has spread to regional lymph nodes.

Metastasis (M): Determines if cancer has spread to distant organs.

Additional factors: Hormone receptor status (ER/PR), HER2 status.

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12
Q

What are the most common respiratory system (lung cancer) tumor types?

A

Small Cell Lung Cancer (SCLC) (10-15%) and Non-Small Cell Lung Cancer (NSCLC) (80-85%)​​.

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13
Q

Who is most likely to develop lung cancer?

A

Smokers, people exposed to radon or asbestos, and those over 65 are at high risk​​.

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14
Q

What are the major anatomic structures involved in lung cancer?

A

The lungs, bronchi, pleura, and mediastinum are involved in lung cancers​.

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15
Q

Is metastatic spread common in lung cancer?

A

Yes, lung cancer often metastasizes to the brain, bones, liver, and adrenal glands​.

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16
Q

What are some common signs and symptoms of head and neck (H&N) cancers?

A

Persistent sore throat, difficulty swallowing, hoarseness, swelling in the neck, and ear pain.

17
Q

What are the risk factors for Head & Neck cancers?

A

Tobacco, alcohol, and HPV infection increase the risk​.

18
Q

What is the most common tumor type in head and neck cancers?

Aka cell type

A

Squamous cell carcinoma (SCC).

19
Q

What are the risk factors for head and neck cancers?

A

Tobacco use, alcohol consumption, HPV infection, and exposure to certain environmental carcinogens.

20
Q

Where do lymph nodes in the lower lip drain?

A

They drain into the submental and submandibular lymph nodes​.

21
Q

What cancers are more prevalent according to the American Cancer Society?

A

Answer: For males: Prostate (21%), Lung (13%), Colorectal (9%).

For females: Breast (30%), Lung (12%), Colorectal (8%)​​.

22
Q

What drugs can cross the blood-brain barrier (BBB)?

A

Fat-soluble chemotherapy drugs like nitrosoureas can cross the BBB​​.

23
Q

What is the most common malignant brain tumor in adults?

A

Glioblastoma Multiforme (GBM) is the most common malignant brain tumor.

6.9% 5 year survival rate

24
Q

What is the difference between primary and secondary brain cancers?

A

Primary brain cancers originate in the brain, while secondary ones metastasize from other areas​​.

25
Q

What is the most common benign Brain tumor overall?

A

Meningioma, a common benign tumor​.

26
Q

What is the TNM staging system used for?

A

TNM is used for estimating the stage of various cancers based on tumor size, lymph node involvement, and metastasis​​.

27
Q

What procedures are used to determine a cancer diagnosis?

A

Biopsy, CT scans, MRI, and PET scans​​.

28
Q

What symptoms are associated with Superior Vena Cava (SVC) syndrome?

A

Swelling in the face and arms, dyspnea, and distended veins in the chest​.

29
Q

What is a radiosensitizer?

A

A radiosensitizer is a drug that enhances the effects of radiation on cancer cells​.