(Midterm) Ointments, Paste, Creams/Suppositories

Question 1

Which of the following statements is true?
1. Vanishing cream is a without emulsion containing small amounts of water
2. Creams find primary application in topical skin products and in products used rectally and vaginally
3. Ointments are preferred more by patients due to ease of spreadability
Show answer choices

Answer 1

2 only

Question 2

Ointment base made form yellow wax and petrolatum

Answer 2

Cold cream

Question 3

Based on the compendial requirement for ointments, what particular microbes should be absent from dermatological products?
1. S. aureus
2. P. aureginosa
3. E. coli

Answer 3

1,2

Question 3

A method of manufacture of anhydrous ointments wherein the active/s are dissolved in the previously melted mixtures of fats and waxes, at controlled temperatures;

Answer 3

Fusion Method

Question 4

Raw materials which are widely used as humectants in semi-solids to prevent “crusting” in ointment and creams contained in jars;
a. all of the choices
b. Propylene glycol
c. Glycerin
d. Sorbitol, 70%

Answer 4

all of the choices

Question 5

An ideal suppository should melt

Answer 5

Within body temperature

Question 6

Also known as hydrocarbon ointment bases

Answer 6

Oleaginous bases

Question 7

The following are advantages of pastes over ointments EXCEPT
a. More absorptive
b. Less greasy
c. Preferred for oozing lesions
d. Easier to spread and remove

Answer 7

Easier to spread and remove

Question 8

Ointment base classified as hydrocarbon base include
1. Petrolatum
2. White ointment
3. Polyethylene Glycol Ointment

Answer 8

1,2

Question 9

Rectal suppositories
1. Pediatric suppositories are more narrow and pencil-shaped than the typical bullet-shaped adult suppository
2. Suppositories intended for females are about half the length and weight of the male counterpart
3. Examples include glycerin suppositories and Bisacodyl suppositories

Answer 9

3 only

Question 10

Suppositories
1. Are solid dosage forms of various weights and shapes, usually medicated, for insertion into the rectum, vagina or urethra
2. Soften, melt, or dissolve in the cavity fluids after insertion
3. Provide local and systematic action

Answer 10

1,2,3

Question 11

The suppository base for vaginal administration

Answer 11

Polyethylene glycol

Question 11

Wecobee bases are derived from

Answer 11

Coconut oil

Question 12

True statements about levigation includes
1. Allows both particle size reduction and dispersion of the substance in vehicle
2. Glycerin is the levigating agent for bases where water is the external phase
3. The amount of the levigating agent should be about equal in volume to the solid material

Answer 12

2 only

Question 13

Referred to as “greaseless” base

Answer 13

Water-soluble base

Question 14

Cocoa butter
1. Exhibits marked polymorphism
2. Phenol and chloral hydrate have a tendency to lower its melting point
3. Is a water-soluble or water-miscible base

Answer 14

1,2

Question 14

Ointment bases that resemble cream in appearance

Answer 14

Water removable base

Question 15

Zinc oxide paste is
1. A very firm product used to protect the skin and absorbs serous secretions
2. Prepared by levigating and mixing 25% each of zinc oxide and starch with white petrolatum
3. Also known as Lassar’s Plain Zinc Paste

Answer 15

1,2,3

Question 16

Cocoa butter is softened due to the addition of certain drugs, which of the following can be added as a solidifying agent?

Answer 16

Beeswax

Question 16

TRUE statements about PEG-based suppositories include
1. Stored at room temperature
2. Leaks from the orifice
3. It dissolves in the body fluid to release the active drug

Answer 16

1,3