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N232 > Midterm module 3 analgesics > Flashcards

Midterm module 3 analgesics Flashcards

1
Q

What are adjuvant analgesics

A

Drugs that are added for combined therapy with a primary drug that may have additive or combined independent properties
(NSAIDs, non-opioid analgesics, anticonvulsants, antidepressants, corticosteroids)

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2
Q

what is the classification of ASA

A

NSAID / Antipyretic

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3
Q

how is ASA available

A

Tablets & suppositories, enteric coated 81mg-975 mg

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4
Q

what are the indications of ASA

A

Inflammatory disorders
mild to mod pain
fever
prophylaxis of TIA & MI

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5
Q

what is the mechanism of action of ASA

A

Inhibiting prostaglandin synthesis, decrease platelets aggregation

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6
Q

what are the side effects of ASA

A

Nausea, Tinnitus, GI bleeding

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7
Q

what are the pre-post checks for ASA

A

Allergies, pain, under 19 should not take post viral infections

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8
Q

what are the teaching aspects of ASA

A

Give with full glass of water, food. Don’t give enteric coated with milk

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9
Q

What is the classification of Ibuprofen

A

NSAID, antipyretic

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10
Q

what is the availability of ibuprofen

A

tablets 200-400mg

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11
Q

what is the indication of ibuprofen

A

Inflammatory disorders, mild to moderate pain, fever

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12
Q

what are the mechanism of action of ibuprofen

A

inhibit prostaglandin synthesis

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13
Q

what are the side effects of ibuprofen

A

nausea, GI bleed, HR MI, stroke

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14
Q

what are the pre checks for ibuprofen

A

Hx of GI bleed, renal insufficiency

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15
Q

what is the teaching for ibuprofen

A

Give with a full glass of water, food avoid alcohol

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16
Q

what is the classification of acetaminophen

A

Non-narcotic analgesic, antipyretic

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17
Q

what is the availability of acetaminophen

A

Tablet, supp. liquid

18
Q

what is the indication of acetaminophen

A

Treatment of mild pain & fever

19
Q

what is the mechanism of action of acetaminophen

A

inhibiting enzymes necessary for prostaglandin synthesis

20
Q

what is the onset of acetaminophen

A

Rapid.

peak = 0.5-2 hr duration is 3-4 hours

21
Q

what are the side effects of acetaminophen

A

hepatoxicity

22
Q

whats the max amount of acetaminphen a day

A

4g

23
Q

what is the classification of gabapentin

A

Analgesic adjuncts, anticonvulsants

24
Q

what are the indications for gabapentin

A

Neuropathic pain, migranes, anxiety & diabetic neuropathy

25
Q

what are the side effects of gabapentin

A

Increased risk of suicidal thoughts & behaviours, confusion, drowsiness

26
Q

what organ should you be concerned about with gabapentin

A

renal

27
Q

what is the teaching for gabapentin

A

May cause dizziness & drowsiness - do not take within 2 hours of antacid. suicidal thoughts

28
Q

what is amitriptyline class

A

antidepressant with unlabelled uses for anxiety & chronic pain

29
Q

what is the mechanism of action for amitriptyline

A

Potentiates the effect of serotonin & NE in the CNS

30
Q

what are the side effects of amitriptyline

A

May increase risk of suicide attempt/ideation, ssedation, leathery, hypotension, constitpation

31
Q

what are the pre checks for amitriptyline

A

BP & Pulse & renal insufficiency

32
Q

what is the teaching for amitriptyline

A

may cause dizziness, blurred vision, monitor suicide

33
Q

what are the high efficacy vs low efficacy narcotics

A 
hi efficacy 
- Morphine sulfate 
-Fentanyl 
-Methadone 
-Dilaudide 
moderate efficacy 
-codeine
34
Q

what is the classification of morphine

A

Opioid analgesic

35
Q

what is the mechanism of action of morphine

A

binds to opiate receptors in the CNS. Alters the perception of & response to painful stimuli while producing generalized CNS depression.

36
Q

what is the onset for morphine

A

Rapid. peak = 60 minutes. Durations - up to 7 hours

37
Q

what are the side effects of morphine

A

respiratory depression & consitpation

38
Q

pre checks for morphine

A

RR, BP

39
Q

what is the mechanism of methadone

A

binds to opiate receptors in the CNS. Alters the perception of & response to painful stimuli while producing generalized CNS depression.

40
Q

what is the indication of methadone

A

Moderate to severe chronic pain in opioid-tolerant patients requiring 24/7 opioid tx

41
Q

basics of equianalgesic opiod conversion for chronic pain

A

-Po is always more than parenteral (around double)

N232 (10 decks)

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