Midterm II Flashcards
Monosaccharides
Simplest form of carb, not usually found in nature
Cant be further hydrolyzed
Ex: glucose, fructose, galactose
Disaccharide
made up of 2 monosaccharide chain units
Sucrose
glucose+fructose (table sugar)
lactose
galactose+glucose (dairy)
maltose
glucose dimer (molasses)
Isomaltose
glucose dimer (amylopectin and glycogen)
Oligosaccharide
multiple monosaccharide units
Ex. Rafinnose->Trisaccharide
Polyshaccharide
10+ monosaccharide units
Ex. starch in grains and cereals
such as amylose, amylopectin, glycogen
Dietary fiber
undigestible polysaccharides and non carb compounds PEctin- fruit lignin-veggie mucilage-grains/cereal glycoprotein-legumes physic acid-nuts
Alpha amylase
digests starch and glycogen into glucose, maltose, isomaltose
Produced by salivary glands and pancreas
SGLT-1
Active Na transport (Na-K pump)
Glut-1
passive-brain kidney, placenta, colon, RBCs
Glut-2
Passive- rapid intestine to blood transport (falconi bickel syndrome)
Glut-3
Passive- brain, kidney, placenta
SGLT-1 and Glut-4
Both active
Glut-1 and Glut 3
both for brain, kidney, placenta
Michaelis Menton Equation (Km)
Km=substrate producing velocity at 1/2 max
-how strong affinity enzyme has for substrate
Low km=high affinity
whole foods diet
decreases pace of glucose absorption
galactokinase
activates galactose to Gal-1-P
Galactose-1-phosphate-uridyl-transferase
transfers galactose from gal-1-p to UDP-glucose forming UDP-GAC
Cooking
increases glycemic index (GI)
increase fiber intake
decreases GI
increase fructose intake in fruit
decreases GI
Increased GI
Increase risk for DM type II
decrease GI
Decreases cholesterol, LDL, and increase HDL
Evidence to support low GI as primary diet
Little exists
Sweetness of sugars
- Fructose
- Sucrose
- glucose
- galactose
- lactose
protein tyrosine kinase
used by insulin, GH, IGF-1, IGF-11
DM blood levels
Random glucose= >140mg/dl
Fasting glucose= >126mg/dl
HbA1c= >8%
Insulins effects on body
Increase glycolysis Decrease gluconeogenesis Increase glycogenesis decrease glycogenolysis increase lipogenesis decrease lipolysis
Adenylate Cyclase
used by epinephrine, calcitonin, and ADH
Epinephrines effects on body
Decrease glycolysis Increase gluconeogenesis increase glycogenolysis decrease glycogenesis decrease lipogenesis Increase lipolysis
Guanylate Cyclase
Used by NO
Hormone Response element
Used by androgens, estrogens