Midterm Flashcards
The genital system develops from the embryonic?
mesoderm
Primary oocytes first appear at what stage
in the primordial follicles
primordial germ cells can be identified in the 3rd week of devel in the ?
yolk sac
Gartner cysts devel from remnants of
Mesonephric ducts
Labia minora develops from?
urogenital folds
Labia majora develops from?
labioscrotal swellings
false and true pelvis are separated by?
by the plane of the?
linea terminalis,
pelvic inlet
diagonal conjugate is defined as the distance?
btwn the lower border of the pubis anteriorly and the lower sacrum at the level of the ischial spines
contains uterine aa., vv., and ureters?
the region btwn ovaries and tubes?
broad ligament;
mesosalpinx
MC pelvic type
gynecoid
narrowest fixed distance through which the fetal head must pass in a vaginal delivery?
should be what measurement?
interspinous diameter;
10cm
Oogonia cease to form after?
birth
fallopian tubes are approx how long?
their blood supply is from?
7-14cm;
ovarian and uterine aa.
distance of ureter from uterine side wall at pt where it crosses uterine a?
1.5-3cm
results in vaginal atresia?
lack of canalization of vaginal plate
innominate bones are cmpsd of the fused ileum, ischium and?
acetabulum
obstetric conjugate should be atleast what measurement?
11cm
the transverse diameter of the pelvic inlet should be?
13cm
IUGR is defined as a birth weight less than what percentile?
10th percentile
about what percent of stillborn infants are found to be growth restricted?
25
rate of growth gen declines after?
37th week
late onset IUGR is commonly assoc w?
uteroplacental insuff
eval. of fetal-placental circ is best assessed w doppler velocimetry of what vessel
Umbilical Artery
Hyperviscosity syndrome assoc w IUGR is defined as a fetal Hct more than?
and is assoc with?
65percent;
heart failure
Is multiparity a risk factor for macrosomia?
yes
minor trauma is seen in about what percent of sexual assault victims?
when should ABXs be offered for Px?
routine Px should also be offered for?
25;
routinely;
Hep B
what percent of victims seek help after sexual assault
55
in order to maximize response of tumor therapy you want the min. number of tumor cells in what phase of cc?
the phase most variable in length and influences how responsive a tumor is to chemo?
G0;
G1
Growth fraction is the number of tumor cells not in what phase?
G0
MOA of alkylating agents
interferes w DNA replication by cross-linking DNA
MOA of plant (vinca) alkaloids?
inhibition of microtubule assembly
Antitumor ABXs act during what phase?
Antimetabolites act during?
all phases;
S
Nephrotoxicity is most strongly assoc w what antineoplastic drug?
Cisplatin
Gene therapy in cancer therapy is designed to?
reintroduce nml DNA into tumor cells
the antimetabolites inhibit?
enzymes necessary for DNA replication
approx what percent of pts w molar preg devel persistent or malignant disease
20
pts w partial molar preg are more likely to present as
a missed abortion
complete molar preg is c/b?
absence of fetal parts on U/S
recurrence rate for gestational trophoblastic disease
2 percent
in US incidence of choriocarcinoma following a molar preg is about?
1 in 40 molar pregs
choriocarcinoma metastasizes through?
hematogenous embolization
the cure rate for a pt w nonmetastatic GTN and a FIGO score of 4 is approx
100 percent
lichen simplex chronicus appearence?
best Tx?
diffusely red to reddish brown ;
antipruritic agents at night and topical steroid
lichen planus description?
should be treated w?
white lacey bands of keratosis ;
topical steroid
Sebborheic dermatitis?
management should include
pale to red to yellowish pink ;
5perc aluminum acetate solution, followed by topical corticosteroid
insertional dysparunia, most likely?
vulvar vestibulitis
Hydrocele is assoc w ?
canal of Nuck
Hidradenomas arise from?
sweat glands
assoc w high urinary oxalic acid concs?
vestibulitis
lichen sclerosis and hyperplastic dystrophy w atypia carry what risk of vulvar ca?
4 percent
mixed acanthosis-lichen sclerosis Tx?
corticosteroid cream for 2-3 weeks then topical steroid
characteristic of acanthosis?
Hyperkeratosis
Paget disease of vulva may be assoc w carcinoma of the?
skin
VIN, usual type, Tx?
laser ablation
spread of SCC of vulva is usually to?
overall incidence of this type of metastasis
regional LNs;
30%
Tx for cancer of Bartholin gland?
radical vulvectomy and bilateral lymphadenectomy
inclusion cyst arises from?
imperfect alignment of childbirth lacerations or episiotomy
of all gyn malignancies: vulvar ca accounts for? and vaginal accts for?
5percent;
1-3
type of leiomyoma MC assoc w abnormal uterine bleeding?
submucosal
type of myoma MC mistaken for adnexal mass?
pedunculated
