Midterm Flashcards

1
Q

The genital system develops from the embryonic?

A

mesoderm

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2
Q

Primary oocytes first appear at what stage

A

in the primordial follicles

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3
Q

primordial germ cells can be identified in the 3rd week of devel in the ?

A

yolk sac

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4
Q

Gartner cysts devel from remnants of

A

Mesonephric ducts

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5
Q

Labia minora develops from?

A

urogenital folds

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6
Q

Labia majora develops from?

A

labioscrotal swellings

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7
Q

false and true pelvis are separated by?

by the plane of the?

A

linea terminalis,

pelvic inlet

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8
Q

diagonal conjugate is defined as the distance?

A

btwn the lower border of the pubis anteriorly and the lower sacrum at the level of the ischial spines

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9
Q

contains uterine aa., vv., and ureters?

the region btwn ovaries and tubes?

A

broad ligament;

mesosalpinx

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10
Q

MC pelvic type

A

gynecoid

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11
Q

narrowest fixed distance through which the fetal head must pass in a vaginal delivery?
should be what measurement?

A

interspinous diameter;

10cm

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12
Q

Oogonia cease to form after?

A

birth

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13
Q

fallopian tubes are approx how long?

their blood supply is from?

A

7-14cm;

ovarian and uterine aa.

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14
Q

distance of ureter from uterine side wall at pt where it crosses uterine a?

A

1.5-3cm

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15
Q

results in vaginal atresia?

A

lack of canalization of vaginal plate

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16
Q

innominate bones are cmpsd of the fused ileum, ischium and?

A

acetabulum

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17
Q

obstetric conjugate should be atleast what measurement?

A

11cm

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18
Q

the transverse diameter of the pelvic inlet should be?

A

13cm

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19
Q

IUGR is defined as a birth weight less than what percentile?

A

10th percentile

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20
Q

about what percent of stillborn infants are found to be growth restricted?

A

25

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21
Q

rate of growth gen declines after?

A

37th week

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22
Q

late onset IUGR is commonly assoc w?

A

uteroplacental insuff

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23
Q

eval. of fetal-placental circ is best assessed w doppler velocimetry of what vessel

A

Umbilical Artery

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24
Q

Hyperviscosity syndrome assoc w IUGR is defined as a fetal Hct more than?
and is assoc with?

A

65percent;

heart failure

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25
Q

Is multiparity a risk factor for macrosomia?

A

yes

26
Q

minor trauma is seen in about what percent of sexual assault victims?
when should ABXs be offered for Px?
routine Px should also be offered for?

A

25;
routinely;
Hep B

27
Q

what percent of victims seek help after sexual assault

A

55

28
Q

in order to maximize response of tumor therapy you want the min. number of tumor cells in what phase of cc?
the phase most variable in length and influences how responsive a tumor is to chemo?

A

G0;

G1

29
Q

Growth fraction is the number of tumor cells not in what phase?

A

G0

30
Q

MOA of alkylating agents

A

interferes w DNA replication by cross-linking DNA

31
Q

MOA of plant (vinca) alkaloids?

A

inhibition of microtubule assembly

32
Q

Antitumor ABXs act during what phase?

Antimetabolites act during?

A

all phases;

S

33
Q

Nephrotoxicity is most strongly assoc w what antineoplastic drug?

A

Cisplatin

34
Q

Gene therapy in cancer therapy is designed to?

A

reintroduce nml DNA into tumor cells

35
Q

the antimetabolites inhibit?

A

enzymes necessary for DNA replication

36
Q

approx what percent of pts w molar preg devel persistent or malignant disease

A

20

37
Q

pts w partial molar preg are more likely to present as

A

a missed abortion

38
Q

complete molar preg is c/b?

A

absence of fetal parts on U/S

39
Q

recurrence rate for gestational trophoblastic disease

A

2 percent

40
Q

in US incidence of choriocarcinoma following a molar preg is about?

A

1 in 40 molar pregs

41
Q

choriocarcinoma metastasizes through?

A

hematogenous embolization

42
Q

the cure rate for a pt w nonmetastatic GTN and a FIGO score of 4 is approx

A

100 percent

43
Q

lichen simplex chronicus appearence?

best Tx?

A

diffusely red to reddish brown ;

antipruritic agents at night and topical steroid

44
Q

lichen planus description?

should be treated w?

A

white lacey bands of keratosis ;

topical steroid

45
Q

Sebborheic dermatitis?

management should include

A

pale to red to yellowish pink ;

5perc aluminum acetate solution, followed by topical corticosteroid

46
Q

insertional dysparunia, most likely?

A

vulvar vestibulitis

47
Q

Hydrocele is assoc w ?

A

canal of Nuck

48
Q

Hidradenomas arise from?

A

sweat glands

49
Q

assoc w high urinary oxalic acid concs?

A

vestibulitis

50
Q

lichen sclerosis and hyperplastic dystrophy w atypia carry what risk of vulvar ca?

A

4 percent

51
Q

mixed acanthosis-lichen sclerosis Tx?

A

corticosteroid cream for 2-3 weeks then topical steroid

52
Q

characteristic of acanthosis?

A

Hyperkeratosis

53
Q

Paget disease of vulva may be assoc w carcinoma of the?

A

skin

54
Q

VIN, usual type, Tx?

A

laser ablation

55
Q

spread of SCC of vulva is usually to?

overall incidence of this type of metastasis

A

regional LNs;

30%

56
Q

Tx for cancer of Bartholin gland?

A

radical vulvectomy and bilateral lymphadenectomy

57
Q

inclusion cyst arises from?

A

imperfect alignment of childbirth lacerations or episiotomy

58
Q

of all gyn malignancies: vulvar ca accounts for? and vaginal accts for?

A

5percent;

1-3

59
Q

type of leiomyoma MC assoc w abnormal uterine bleeding?

A

submucosal

60
Q

type of myoma MC mistaken for adnexal mass?

A

pedunculated