Midterm 4 Digestion Flashcards
What is the function of colon?
reabsorption of water and electrolytes
reabsorption of amino acids
secretion of cellulose cleaving enzymes
catabolism of proteins
Reabsorption of water and electrolytes
Which products of microbial fermentation can be utilized by ruminants?
proteins
cellulose
volatile fatty acid
vitamins and volatile fatty acid
Vitamins and volatile fatty acids
Which statement is true for the plexus submucosus?
plexus submucosus controls the local circulation, the secretion and the absorption
it regulates peristalsis
it increases the speed of peristalsis
it controls the intestinal movements
Plexus submucosus controls the local circulation, the secretion and the absorption
What is needed for B12 vitamin absorption?
R protein
proteinX
transcortin
transcorrin
Transcorrin
How can H+ ions get into the lumen of the stomach?
H+ ions originating from the dissociaton of water, get into the lumen by the H+/Cl- pump found in the luminal membrane of the oxyntic (parietal) cells
H+ ions originating from the dissociation of carbonic acid, get into the lumen by the H+/K + pump found in the luminal membrane of the oxyntic (parietal) cells
H+ ions originating from the dissociation of metabolic water, get into the lumen by the H+/K+ pump
the H+/Cl- pump is found in the luminal membrane of the chief cells
H+ ions originating from the dissociation of metabolic water, get into the lumen by the H+/K+ pump
Where does the gas go from the esophagus during the eructation?
mainly into the spaces of the lung
through the oral cavity to the outside
through the nasal cavity to the outside
through the oral cavity and the nasal cavity to the outside
mainly into the spaces of the lung
How many ciliary bacteria can be found physiologically in 1 ml rumen fluid?
10 thousand
1 million
1 billion
10 billion
1 million
Which species has the shortest passage time?
horse
sheep
swine
cattle
Swine
Which plasma factor determines food uptake?
glucose
hormones
volatile fatty acids
temperature of circulating blood
Glucose
Why is the intragastric pressure constant during filling?
because of automatic contraction
it is the result of regulated muscle function
it can be explained by the law of Laplace
the intragastric pressure is kept constant by sympathetic innervation
It can be explained by the law of Laplace
Which products of microbial fermentation can be utilized by monogastric herbivores?
proteins
amino acids
volatile fatty acid
vitamines
Volatile fatty acid
How does n.vagus influence the forestomach?
the ventral branch of vagus supplies the reticulum first
the ventral branch of vagus supplies the rumen
vagus is the nerve of the abomasum only
in ruminants the vagus only supplies the intestines
the ventral branch of vagus supplies the reticulum first
Is the high lactic acid content in the ruminoreticulum advantageous for the animal?
yes, because it transforms to propionic acid easily
no, because it harms mucous membrane and creates acidosis
yes, because it serves as energy source
yes, because it stimulates the absorption of glucose
no, because it harms mucous membrane and creates acidosis
What is happening during vomiting?
repeated expiration with closed glottis
intrapulmonary pressure falls
repeated expiration with opened cardia
repeated increase of the intrathoracic pressure
Repeated increase of the intrathoracic pressure
What reduces the absorption of nutrients?
cholecystochinin, glucagon
low estrogen level
emptying of the digestive tract
reduction of temperature of the circulating blood
Cholecystochinin, glucagon
What binds the iron cations in the lumen of the intestines?
transferrin
transcorrin
ferritin
hemosiderin
Transferrin
where does the gastric mixing movement begin?
from the middle of the corpus
from the cardia
from the antrum
from the pylorus
From the middle of the corpus
What is a tonic contraction of gastrointestinal smooth muscle cells?
contraction of the gastrointestinal canal for minutes, maybe hours
typical, rhythmical contraction of the gastrointestinal canal
movement due to slow waves
movement due to increase of the membrane potential
Contraction of the gastrointestinal canal for minutes, maybe hours
What material stimulates the function of villi?
villikinin
cholecystokinin
VIP
gastrin
Villikinin
What is the role of transcobalamin 1?
keeping cobalamin in the plasma
take cobalamin into the liver
take cobalamin into the cells
take cobalamin into the kidneys
Keeping cobalamin in the plasma
Transcobalamin I (TCN1), also known as haptocorrin, R-factor, and R-protein
which bacterium do organic acids digest in the rumen?
Veilonella gasogenes
Bacterioides ruminicola
Lahnospira multiparus
Bacterioides ruminantium
Veilonella gasogenes
What does “passage time” mean?
duration of food in the gut
microbial digestion time of food
duration of food in the stomach
resorption time of food
Duration of food in the gut
Which species receive maternal immunity partly via the placenta and partly from the colostrum?
Primates
lepidae
ruminants
predators
Predators?
Where is the mucosal coating of the small intestines produced?
in the Lieberkühn glands
in the apical region of the intestinal villi
in the Brunner’s glands
in the aged enterocytes
In the Brunner’s glands
What does pancreatic amylase split?
chain ending peptide bonds
alpha-1-4 bonds
all saccharides
beta-1-4 bonds
alpha-1-4-glycosidic bonds (straight starch chain)
Which hormone stimulates gastric emptying?
secretin
CCK
VIP
gastrin
Gastrin
How do the chylomicrons leave the enterocyte?
by dissolvement on the basal membrane
by exocytosis on the basal membrane
by dissolvement on the lateral membrane
by exocytosis on the lateral membrane
By exocytosis on the lateral membrane
What is the effect of pain in the intestine tract?
dilatation of the colon
total paralysis
a strong contraction of colon
acceleration of peristalsis
Total paralysis
Which statement is true for the rumen?
40 C degrees temperature, aerobic, pH neutral
40 C degrees temperature, anaerobic, pH acidic
40 C degrees temperature, anaerobic, pH basic
40 C degrees temperature, anaerobic, pH neutral
40 C degrees temperature, anaerobic, pH neutral
In which part of the alimentary canal are immunoglobulines taken up?
small intestine
large intestine
stomach
appendix
Small intestine
What causes the gastric emptying?
sympathetic stimulation
activity of the prepyloric part of antrum
pressure difference between duodenum and stomach
peristalsis of the fundus
Pressure difference between duodenum and stomach
Where does the digestion of cellulose in the rabbit take place?
stomach
small intestine
colon
cecum
Cecum
What substance in the piglet has a very low production in newborns but a relatively higher one at 2-3 weeks of age?
salivary amylase
enzymes of the small intestine
enzymes of the pancreas
pepsine
Salivary amylase
Where is the satiety centre?
in the prefrontal cortex
in the amygdala
in the nucl. ventrolateralis of hypothalamus
in the nucl. ventromedialis of hypothalamus
In the nucl. ventroMEDIALIS of the hypothalamus
Where does the absorption of Ca2+ and Mg2+ occur?
intestinum crassum
only in the ileum
both intestinum crassum and tenue
in the fore-part of intestinum tenue
In the fore-part of intestinum tenue
Which species has the largest stomach?
horse
cattle
swine
dog
Cattle
What is typical of saliva production in ruminants?
it is continuous
it is triggered only by feeding
aldosterone does not influence the composition of the saliva
stimulation of the tongue’s mechanoreceptors is necessary for saliva production
It is continuous
What is the main mediator of the increase pancreatic secretion if the intestines contain large amounts of fat or peptide?
secretin
gastrin
CCK
transcorrine
CCK
What part of small intestine has primary pacemaker activity?
ileum
jejunum
duodenum
ileum and jejunum
Duodenum
Which statement is true for the plexus myentericus?
It controls the local circulation
it controls secretion
it controls absorption
it stimulates hormone production
It controls absorption
What increases the absorption of nutrients?
ovariectomy
low insulin level
filling of the digestive tract
increased temperature of the circulating blood
Ovariectomy
What is the composition of the eructated gas?
50% methane, 25% carbon-dioxide, 10% nitrogen, 5% oxygen
50% carbon-dioxide, 25% oxygen, 10% nitrogen, 5% methane
50% nitrogen, 25% carbon-dioxide, methane, 10%, 5% oxygen
50% carbon- dioxide, 25% methane, 10% nitrogen, 5% oxygen
50% carbon- dioxide, 25% methane, 10% nitrogen, 5% oxygen
How can phosphate and bicarbonate get into the primary saliva in ruminants?
through passive diffusion
through active secretion
by exocytosis
the primary saliva does not contain a significant quantity bicarbonate
Through active secretion
Where is absorbed the vitamin B12 in the alimentary tract?
stomach
ileum
duodenum
jejunum
Ileum
What is true for lecithin and cholesterol?
the lecithin is in the micelles
the cholesterol is in the outer sheath of the micelles
the cholesterol is amphoteric
the lecithin increases the dissolved amount of cholesterol in the micelles
the lecithin increases the dissolved amount of cholesterol in the micelles
9 Which bacterium does cellulose digest in the rumen? Veilonella gasogenes Bacterioides ruminicola Bacterioides succinogenes Bacterioides ruminantium
Bacterioides succinogenes
Which is the major control mechanism for gastric movement?
bulbus duodeni
intrinsic regulation
extrinsic regulation
hormonal feed-back
Intrinsic regulation
What material inhibits the contraction of nonstriated muscle of the jejunum?
secretin
cholecystokinin
GIP
gastrin
Secretin
Which pH helps the volatile fatty acids absorb?
neutral
acidic
basic
it is independent of the pH
Acidic (<7)
How much is the pH optimum of the pepsin?
- 2 - 8.6
- 3 -2.2
- 8 - 3.8
- 8 - 4
1.8 - 3.8
What is the task of apolipoprotein B48?
signalling the LDL
it is the activator of lipoprotein lipase in the wall of capillaries
it takes part only in the composition of micelles
it is a signal protein on the surface of “remnant” chylomicrones
It is a signal protein on the surface of “remnant” chylomicrones
How does the parasympathetic influence affect the gastrointestinal smooth muscle cells?
acetylcholine hyperpolarizes the cells
acetylcholine stimulates epinephrine action
acetylcholine depolarizes smooth muscles
acetylcholine hyperpolarizes arteriolar smooth muscles
ACh depolarizes smooth muscles
Which part of small intestine is emptied the slowest?
ileum
jejunum
duodenum
ileum and jejunum
Ileum
What is the pH in the small intestines ?
8,2-8,6
6,2-6,7
2,6-3,6
7,2-7,6
7,2-7,6
Where is a pacemaker of the intestine situated?
in the middle portion of the colon
in the beginning of caecum
in the beginning and end of caecum
in the beginning and end of colon
In the beginning and end of colon?
What kind of chemical mediator increases the bicarbonate concentration in the bile?
secretin
gastrin
CCK
GIP
Secretin
What happens with the saliva in the tubules of the salivary gland?
Na+ and Cl- are secreted and the K+ and HCO3- are partly reabsorbed
Na+ and Cl- are partly reabsorpted and the K+ and HCO3- are secreted
Na+ and K+ are partly reabsorpted and the Cl- and HCO3- are secreted
Na+ and HCO3 are partly reabsopted and the K+ and Cl- are secreted
Na+ and Cl- are partly reabsorpted and the K+ and HCO3- are secreted
Where do the carboxy-peptidases split?
on the C terminal
arginine or lysine containing bonds
tyrosine or phenylalanine containing bonds
phenylalanine, tyrosine and histidine containing bonds
On the C terminal
What is the main buffer in the colon of dogs and cats?
bicarbonate
phosphate
both bicarbonate and phosphate are important
ammonium
Phosphate
Where is the center responsible for chewing?
in the brain stem
in the nucl. Ventromedialis in the hypothalamus
in the cortex
in the spinal cord
In the brain stem (Trigeminal nerve)
What is the main mediator of the increased bicarbonate production of the pancreas?
secretin
gastrin
CCK
CCK and gastrin
Secretin
Which pH helps ammonia absorb?
neutral
acidic
basic
it is independent of the pH
Basic (>7)
In which animal family do we find an Oddi-sphincter?
carnivores
ruminants
monogastric herbivores
horses
Carnivores
How does glucose absorption occur in the small intestine?
With facilitated passive transport
with the support of GLUT 2 transporter
with calcium dependent secondary active transport
with simple diffusion
With calcium dependent secondary active transport
Is there fat digestion in the stomach of an adult mammals?
no, because the pH of the stomach does not allow this type of digestion
no, because the stomach does not produce fat cleaving enzymes
yes, very intensive fat cleaving occurs in the stomach
the G-lipase splits the fat in the stomach, but not to an significant extent
The G-lipase splits the fat in the stomach, but not to a significant extent
What statement is correct for the intestinal phase of gastric secretion?
it is regulated exclusively by the vagus nerve
somatostatin increases the stomach secretion
GIP, VIP, CCK and secretin inhibit the gastric function
CCK, VIP and secretin increase the gastric motility
GIP, VIP, CCK and secretin inhibit the gastric function
How many slow peristaltic waves occur per minute?
8-12
4-5
3-5
1-2
4-5
At which membrane potential are spike potentials produced?
5-15mV
3-12mV
-90mV
-40mV
-40mV
Which immunoglobulin is present in saliva?
IgA
IgD
IgE and IgM
IgG
IgA
What do the Entodinium species digest in the rumen?
chlorophyll
fat
amylose
cellulose
Chlorophyll
what group of animals has the fastest movement in the colon?
ruminants
carnivorous animals, because of aboral mass peristalsis
horses, because of the colon’s antiperistaltic activity
herbivorous animals
Carnivorous animals because of aboral mass peristalsis
In ruminants where do light boluses end up?
to the dorsal sac of the rumen
to the ventral sac of the rumen
to the cranial sac of the rumen
to the reticulum
To the dorsal sac of the rumen
Where do immunoglobulines go after exocytosis?
into lymph and intercellular channels
into capillaries
into enterocytes
into the lumen of intestine
Into capillaries
What is the direct stimulus for secretin secretion?
inhibition of gastric emptying
high intraluminal pressure
low fat content in the small intestine
low pH in duodenum
Low pH in the duodenum
What is a secondary bile acid?
bile acids conjugated with taurine and glycine
dehydroxylated bile products by bacteria of the intestines
decarboxylated products in the intestines
cholic acid and chenodeoxycholic acid
Dehydroxylated bile products by bacteria of the intestines
What does the central nervous system consist of?
the plexus submucosus (Meissneri)
the plexus myentericus (Auerbachi)
the plexus submucosus
the plexus submucosus (Meissneri) and the plexus myentericus (Auerbachi)
The plexus submucosus and the plexus myentericus
Which phase is the suction phase of the reticulo- omasicum?
Phase 1
Phase 3
phase 2
phase 2-3
Phase 1
Which species has the largest proportion of gut in comparison to their body-length?
horse
swine
cattle
dog
Cattle (ruminents in general)
Do cats or dogs eat more frequently?
dogs, in one sitting they can eat more than 10% of their body weight
dogs eat more per body weight
cats eat more frequently, but eat less than dogs per body weight
no difference
Cats east more frequently, but eat less than dogs per body weight
What is the difference between serous and mucous saliva?
their composition is not significantly different
their viscosity differs
their electrolyte composition differs
they contain different enzymes
Their viscosity differs
What kind of Na+ transport is not found on the luminal side of the enterocyte?
Na+ - Cl- cotransport
cotransport of Na+ and other kinds of organic substances
absorption of Na+ by itself
Na+ -K+ antiport
Na+ -K+ antiport
Which factor enlarges the absorbing surface of the intestinal tract?
the surface of the intestinal tract as a tube
the folded nature of the inner surface of the intestinal tract
the presence of intestinal villi
the presence of the brush border
The presence of the brush border
Which reflex does not depend on the sympathetic ganglion?
defecation
gastric-colon
colon-gastric
intestine-colon
Defecation
Where can you find the bile canaliculi?
in the gall-bladder
in the sinusoids of the liver
in the perisinusoid fissures
between the two columns of hepatic cells
Between the two columns of hepatic cells
Where does the biphasic contraction of the reticulum send the light food contents of reticulum?
to dorsal sac of rumen
to ventral sac of rumen
to cranial sac of rumen
to caudal sac of rumen
Dorsal sac of rumen
Which material stimulates the cell division in the gut the most?
gastrin
secretin
GIP
CCK
Gastrin