Midterm 2 Flashcards
- Which of the following statements correctly describes endocrine glands?
a. They produce hormones into the ducts.
b. They act locally on nearby tissues.
c. They all can pass through the plasma membrane.
d. They are all controlled by the nervous system.
b
- Which of the following statements correctly describes hormones?
a. They are all of similar chemical composition.
b. They combine with specific receptors on the target cell’s surface or inside the target cell.
c. They are secreted at a constant rate.
d. They all act by activating adenylate cyclase, which transforms ATP into cyclic AMP.
b
- Which of these statements does NOT correctly describe hormones?
a. Multiple hormones may be produced by a single endocrine gland.
b. More than one hormone may influence a single target cell.
c. A single hormone can influence only one type of target cell.
d. Hormones may be secreted by an endocrine organ that may also exert nonendocrine functions.
b
- Which of these statements does NOT apply to peptide hormones?
a. They include adrenal cortex hormones.
b. Insulin is an example of this type of hormone.
c. They are stored within secretory granules.
d. They are secreted from endocrine glands.
a
- Which of the following statements correctly describes tropic hormones?
a. They are produced by the posterior pituitary.
b. They are secreted only by the hypothalamus.
c. They primarily regulate hormone secretion by certain other endocrine glands.
d. They all have non-tropic functions too.
c
- Which class of hormones is synthesized by the endoplasmic reticulum–Golgi complex mechanism?
a. peptides
b. catecholamines
c. steroids
d. thyroid hormones
a
- Which of these hormones is NOT a tropic hormone?
a. ACTH
b. ADH
c. ICSH
d. LH
b
- Which class of hormones is released by exocytosis upon appropriate stimulation?
a. peptides
b. thyroxins
c. steroids
d. insulins
a
- The transport of lipid-soluble hormones in the blood is accomplished by which of the following mechanisms?
a. loose binding with iodine
b. specific binding to some plasma proteins
c. binding to HDLs
d. binding to glycolipids
b
- Which of the following statements is correct with respect to steroids?
a. They are hydrophilic.
b. They are derived from cholesterol.
c. They initiate synthesis of the second messenger system within their target cells.
d. Epinephrine is an example of a steroid.
b
- Which class of hormones acts by means of a second-messenger system?
a. proteins
b. catecholamines
c. steroids
d. thyroid hormones
b
- Which of the following substances is the most common second messenger used by hydrophilic hormones?
a. calcium
b. cyclic AMP
c. chromatin
d. messenger RNA
b
- Estrogens, testosterone, cortisol, and aldosterone are derivatives of which molecular precursor?
a. DHEA
b. cholesterol
c. UDP-glucose
d. epinephrine
b
- Which of the following happens in the second-messenger step?
a. A small amount of one hormone (the second messenger) is required to release another.
b. A tropic hormone (the first messenger) stimulates secretion of another hormone (the second messenger).
c. The hormone first binds to a specific surface receptor, whereupon the hormone–receptor complex moves into the cell to combine with a specific intracellular receptor.
d. A hormone (the first messenger) binds to surface receptors, activating adenylyl cyclase, which catalyzes cAMP formation.
d
- Which of the following can influence the effective plasma concentration of a hormone?
a. the hormone’s rate of binding to receptors on target tissues
b. the hormone’s extent of binding to plasma proteins
c. the hormone’s rate of metabolic activity
d. the hormone’s rate of secretion
d
- Which of the following statements applies to TSH?
a. A build-up of the thyroid hormone stimulates its production by negative feedback.
b. It is secreted by the thyroid gland.
c. It is stored in the posterior pituitary.
d. It stimulates the thyroid gland.
d
- Which of the following statements correctly describes control of hormone secretion?
a. Normally the effective plasma concentration of a hormone is regulated by the rate of its synthesis.
b. In order to maintain homeostasis, the rate of hormone secretion remains constant.
c. All hormones are regulated with negative feedback controls.
d. Neuroendocrine reflexes produce a sudden increase in hormone secretion in response to a specific, usually external, stimulus.
d
- Which of the following statements refers to permissiveness of hormones?
a. Hormones permit cellular processes to occur.
b. Hormones permit their target organs to function at the optimal rate.
c. In some instances, an adequate amount of one hormone must be present for the full exertion of another hormone’s effect.
d. Through numerous neuroendocrine relationships, the nervous system allows the endocrine system to function.
c
- Which of the following statements applies to the posterior pituitary?
a. It secretes ADH.
b. It stores anterior pituitary hormones.
c. It stores ACTH and LH.
d. It secretes vasopressin and oxytocin into the hypothalamic–hypophyseal portal system.
d
- Which of these hormones is a neurohormone?
a. vasopressin
b. thyroid hormone
c. growth hormone
d. cortisol
a
- Which one of the following hormones is released from the hypothalamus?
a. CRH
b. TSH
c. FS
d. LH
a
- Which of the following statements correctly describes the anterior pituitary?
a. It is also known as the neurohypophysis.
b. It is composed primarily of nervous tissue.
c. It primarily secretes tropic hormones.
d. It secretes vasopressin
c
- Which of the following statements correctly describes hypophysiotropic hormones?
a. Each hypophysiotropic hormone influences only one anterior pituitary hormone.
b. All hypophysiotropic hormones stimulate the release of anterior pituitary hormones.
c. Hypophysiotropic hormones are also produced outside the hypothalamus, where they serve different functions.
d. Hypophysiotropic hormones are secreted into the general circulation.
c
- Which of these activities happens in a short-loop, negative-feedback, control system?
a. The anterior pituitary hormone feeds back to the hypothalamus, suppressing releasing hormone.
b. The target gland’s hormone feeds back to the anterior pituitary, suppressing the tropic hormone.
c. The target gland’s hormone does not feed back to any other gland.
d. The anterior pituitary hormone feeds back to the posterior pituitary gland, stimulating the inhibiting hormone.
a
- Which of these statements represents long-loop, negative feedback in the CRH–ACTH–cortisol system?
a. Cortisol inhibits CRH secretion.
b. CRH inhibits ACTH secretion.
c. ACTH inhibits CRH secretion.
d. ACTH inhibits cortisol secretion.
a
What does the zona glomerulosa of the adrenal cortex secrete?
a. aldosterone
b. cortisol
c. androgens and estrogens
d. epinephrine
a
Which statement concerning adrenocortical hormones is INCORRECT?
a. The glucocorticoids are examples.
b. Some are steroids.
c. They are all controlled primarily by TSH.
d. They are secreted from the outer layer of the adrenal gland.
c
- What is the most abundant and physiologically important adrenal sex hormone?
a. aldosterone
b. cortisol
c. dehydroepiandrosterone
d. estradiol
c
. Which statement is correct for aldosterone?
a. It causes conservation of sodium.
b. It facilitates lipolysis.
c. It promotes gluconeogenesis.
d. It is regulated by ACTH.
a
Which of the following does NOT regulate aldosterone secretion?
a. ACTH
b. the renin-angiotensin system, which is activated by various factors related to a fall in plasma Na+ concentration/ECF volume/arterial blood pressure
c. the direct effect of plasma K+ on the adrenal cortex
a
- What would a drop in blood pressure be expected to lead to?
a. increased plasma aldosterone levels
b. increased glucocorticoid levels
c. decreased plasma aldosterone levels
d. decreased glucocorticoid levels
a
- What is NOT an action of cortisol?
a. increasing the conversion of glycogen to glucose
b. stimulating gluconeogenesis in the liver
c. increasing protein degradation
d. mobilizing fat from adipose tissue
a
Which two hormones are produced from the same large precursor molecule, pro-opiomelanocortin?
a. aldosterone, cortisol
b. cortisol, androgen
c. cortisol, beta endorphin
d. aldosterone, androgen
c
Which statement is NOT true for cortisol?
a. It is the primary mineralocorticoid.
b. Its excess is responsible for Cushing’s syndrome.
c. It increases blood glucose, blood fatty acid, and blood amino acid levels.
a
When a student experiences psychological and emotional stress, what won’t they secrete at higher levels?
a. GRH
b. ACTH
c. cortisol
a
What is the major factor that promotes increased secretion of cortisol from the adrenal cortex?
a. low Na+ concentration in the extracellular fluid
b. physical and emotional stress
c. angiotensin II
d. increased blood amino acid concentration
b
Which of the following is NOT characteristic of Cushing’s syndrome?
a. hypernatremia
b. hyperglycemia
c. muscle weakness and fatigue
d. poor wound healing
a
. Because aldosterone encourages K+ secretion into the urine, what does conditions in which excess aldosterone is secreted result in?
a. hyponatremia.
b. hypokalemia.
c. hypotension.
d. idiopathic atrophy.
b
Which of the following is NOT seen in Addison’s disease?
a. marked Na+ loss in the urine
b. lowered blood glucose levels
c. K+ retention
d. protein mobilization
d
Which of the following is characteristic of Conn’s syndrome?
a. K+ increase in the blood
b. Na+ depletion
c. hypertension
c