Midterm 1 Flashcards
What are the two types of cells that make up the Nervous System?
Neurons and Glial cells
What are the four types of glial cells?
Astrocytes, Oligodendrocytes, Schwann cells, and Microglia
What is the function of astrocytes?
INPUT
What is the function of oligodendrocytes?
They produce the myelin sheaths over the axons of neurons
What is the function of shwann cells?
They do the same function as the oligodendrocytes, but in the peripheral nervous system
What is the function of microglia?
They act as immune response (macrophages) in the CNS
Describe the anatomy of a neuron
Dendritic spines in the dendrite receive information from other neurons. This leads towards the cell body, toward the axon hilock
What are the Nodes of Ranvier?
These are the spaces between myelin sheaths on axons. These are the areas still exposed to extracellular space, allowing for action potentials to refresh upon moving through mylenated areas of the axon.
What are the other two terms to describe cell bodies?
Cell bodies are also called nucleus in the CNS, and ganglion in the PNS
What is the purpose of dendritic spines?
The dendritic spines are the membrane in the dendrites that receive information from another cell
Do nerve impulses travel faster down larger or smaller axons? Why?
Nerve impulses travel faster down larger axons due to larger surface area, meaning more sodium channels to induce action potentials
What are multipolar neurons?
Multipolar neurons make up a majority of neurons in the nervous system. They are neurons that have a single axon and many dendrites
What are monopolar neurons and where are they found?
Monopolar neurons are neurons with a single branch that leaves the soma, which can then branch into the dendrites or terminal. These can be found
What is the resting membrane of a neuron? Why?
-70mV, negative on the inside and positive on outside due to sodium concentration differences.
What is electrostatic force in neurons?
Electrostatic force is the force that moves ion and particles based on the properties of charged ions (opposites attract, like repel)
What is the Nernst equation used for?
The Nernst equation is used to determine the charge of ions in and out of the cell
Explain action potentials moving down a cell
Input leads to the neuron getting more positive until it reaches threshold, where the Na+ gates open to let Na+ in and raising the potential to a peak. Upon reaching some positive potential, K+ gates open to let K+ out and Na+ channels close. Potential slowly falls. This repeats at areas of the axon along a neuron.
What are synapse? What are the two types of synapse?
Synapses are connections between neurons. There are chemical synapses and electrical synapse
How does a patch-clamp work?
A patch-clamp studies the change in charges of cells when a solution that is high in concentration of some ion.
How does a chemical transmission at a synapse occur?
When an action potential reaches the terminal buttons, Ca++ gates open and influx of Ca++ ions cause vesicles to bind to the membrane of the presynaptic neuron. The NT are released to the receptors on the post-synaptic neuron.
What are the most and least common synapses?
Axo-spinous and axo-dendritic are common but weak, while axo-axonic and dendro-dendritic synapses are least common (but powerful)
What happens to a neurotransmitter in the synapse after conduction of the action potential?
Reuptake of leftover neurotransmitters into the cytoplasm or degraded
What are the two types of receptors?
Ionotropic (ion connects with receptor, and receptor opens gate)
Metabotropic (second messenger G protein)
Sagittal
Split left and right