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Endocrinology > Midterm 1 > Flashcards

Midterm 1 Flashcards

1
Q

What snips off the arginine and leusine in polypeptide biosynthesis?

A

A carbonyl peptidase H

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2
Q

What cells are in the a cells category of anterior pituitary

A

Lactotrope and somatotrope

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3
Q

What is the name of the cells of the B cells anterior pituitary

A

Gonadotropes and thyrotropes

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4
Q

What is the name of the cell that is chromophobe in anterior pituitary

A

Corticotrope

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5
Q

What are the three gene families and what cells do they correspond to?

A

A- GH and PL, B- FSH/LH/TSH, C- ACTH

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6
Q

What hormones come from magnocellular?

A

Vasopressin or oxytocin

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7
Q

Which originate from parvocellular?

A

Releasing factors

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8
Q

What hormone is from the somatotrope?

A

Growth hormone

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9
Q

Which hormone inhibits prolactin?

A

Dopamine

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10
Q

Which type of cell is responsible for prolactin?

A

Lactotrope

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11
Q

Which hormone is released from the hypothalamus into the anterior pituitary in gonadotrope?

A

GnRH

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12
Q

What hormones are released by the gonadotrope?

A

LH and FSH

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13
Q

Which hormone is released by corticotrope?

A

ACTH

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14
Q

What turns on ACTH release?

A

CRH

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15
Q

What turns off ACTH release?

A

AVP

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16
Q

What does phosphodiesterase do in the cAMP/PKA pathway?

A

It breaks down cAMP

17
Q

What does phospholipids C do for the IP3/DAG pathway?

A

Breaks down IP3/DAG

18
Q

What does IP3 do?

A

Bonds to calcium channel to release it

19
Q

What does calcium do in IP3/DAG do?

A

Binds to calmodulin and PKC to cause an effect through phosphorylation

20
Q

What does DAG do?

A

Activates PKC

21
Q

What takes the tyrosine receptors to be degraded?

A

Ubiquitin

22
Q

Which is the insulin pathway?

A

Tyrosine kinase 2

23
Q

What does thyroid bind to and what comes off in mode of action?

A

Thyroid receptor, inhibitor comes off + goes on

Endocrinology (4 decks)

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