Microtubule Accessory Proteins Flashcards
Stathmin
Binds tubulin subunits stops them form assembling
gamma (y)-TuRC
Is concentrated in the centrosome.
Centrisome
Has the centrioles within it
pericentriolar material outside
Ringed with gamma - TuRC
+TIPs
Remains associated with the growing plus end and can link them to others structures such as membranes. This allows the microtubule to still grow and push off or push a structure
XMAP215
XMAP215 accelerates growth of + end of the microtubule by stabilizing it through binding
MAPs
Stabilizes the whole microtubule by binding along its sides.
Katanin
Severs microtubules like a katana!
Plectin
Links intermediate filaments to microtubules
Kinesin-13
causes catastrophe for microtubules
Tau
links with microtubules in a close proximity. It is only in the axon
MAP2
Binds in a spread out fashion and exists in the soma and dendrites
EB1 protein
Is a capping protein that binds with Kar9 protein.