Microscopy findings Flashcards
Light microscopy: proximal tubule with lipids & proteins
MINIMAL CHANGE DZ
Light Microscopy: segmental sclerosis of few glomeruli
FOCAL SEG GLOMERU SCLEROSIS
Immunofluorescence: + IgM & C3
FOCAL SEG GLOMERU SCLEROSIS
Light Microscopy: thickened basement membrane and “spike & dome”
MEMBRANOUS GLOMERULONEPHROPATHY
Immunofluorescence: granular pattern & IgG
MEMBRANOUS GLOMERULONEPHROPATHY
Electron Micros: subepithelial immune complex
MEMBRANOUS GLOMERULONEPHROPATHY
Light microscopy: diffuse glomerulosclerosis (thickening of the basement membrane)
DIABETIC NEPHROPATHY
Light microscopy: “lumpy bumpy” appearance and glom have inc # cells
POSTINFECTIOUS GLOMERULONEPHRITIS
Immunofluorescence: granular pattern, + for IgG, IgM & complement
POSTINFECTIOUS GLOMERULONEPHRITIS
Electron: immune complex deposition
POSTINFECTIOUS GLOMERULONEPHRITIS
Cortex is pale and swollen
CHRONIC GLOMERULONEPHRITIS
Light microscopy: Focal segmental glomerulosclerosis of crescentic glomerulonephritis
IgA NEPHROPATHY
Immunofluorescence: Granular pattern with IgA and complement
IgA NEPHROPATHY
Electron microscopy : IgA
IgA NEPHROPATHY
Microscopic findings: Edema of cells, neutrophils, focal necrotizing infiltrates
ACUTE TUBULOINTERSTITAL DISEASE