Microscopy

Question 1

germinal centre

Answer 1

The germinal center (GC) is a specialized microstructure that forms in secondary lymphoid tissues, producing long-lived antibody secreting plasma cells and memory B cells, which can provide protection against reinfection

Question 2

HEV

Answer 2

High endothelial venules (HEVs) are blood vessels especially adapted for lymphocyte trafficking which are normally found in secondary lymphoid organs such as lymph nodes (LN) and Peyer’s patches

Question 3

Which 3 processes relevant for the humoral immune response take place in the germinal centers of the B cell follicles

Answer 3

1. somatic hypermutation
2. isotype switching
3. memory cell production

Question 4

vessels at the hilus of LNs

Answer 4

1. efferent lymphatic vessel
2. vein
3. artery

afferent vessels are found at the outercrotical area of the LN