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Hematology Lab > Microhematocrits, Hemoglobin, and RBC Indices > Flashcards

Microhematocrits, Hemoglobin, and RBC Indices Flashcards

1
Q

Packed cell volume (PVC) is also known as…

A

 hematocrit (Hct.) 

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2
Q

A quaternary protein, transports oxygen from the alveoli to the tissues of the entire body, and resides in circulating RBCs 

A

Hemoglobin

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3
Q

The volume of RBCs in a given volume of blood. It is expressed as a percentage of the total blood volume

A

Hematocrit

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4
Q

What is a classical method of determining the hematocrit

A

“Spun hematocrit or spun crit”

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5
Q

What is a good estimate of the hematocrit that can be obtained by indirect methods? 

A

Measuring hemoglobin and multiplying this value by three

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6
Q

Manual hematocrit should be performed within ____ hours After blood collection. 

A

6

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7
Q

What effect can increased concentration of EDTA (or other Anticoagulants) have? 

A

Cause shrinking and osmotic crenation of RBCs

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8
Q

Conditions that increase the turbidity of the plasma (lipemia or Leukocytosis), Will affect the results in what way?

A

Artificially increase the absorbents and yield a falsely high hemoglobin result

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9
Q

What effect will “lyse-Resistant” RBCs have on hematocrit results?

A

Falsely decreased hemoglobin result

(Hgb C and Hgb S) 

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10
Q

What is the equation for the “rule of three?“?

A

Hgb x 3 = Target range of Hct (+/-3.0%)

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11
Q

What are two possibilities if the H&H (Hgb and Hct) do not match? 

A

• there is an instrumentation or operator problem
• The RBCs are abnormal

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12
Q

If the RBCs on a peripheral blood smear appear normal, but the automated H&H values do not match, what should the lab personnel do?

A

Check to make sure that an error has not occurred

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13
Q

What is the rule of three used to assess?

A

The integrity of the hemoglobin and/or hematocrit measurements

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14
Q

A “hemogram” consist of what tests? 

A

WBC count
RBC count
Hemoglobin (Hgb)
Hematocrit (Hct)
MCV
MCH
MCHC
PLT

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15
Q

What are three sophisticated instrumentation Devices that are sometimes added to the hemagram in hospitals?

A

• RDW (Red cell distribution width)
• MPV (Mean platelet volume)
• PDW (Platelet distribution width) 

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16
Q

Total erythrocyte (RBC) count , Hgb and Hct values are used to determine what three RBC indices?

A

•mean cell/corpuscular volume (MCV)
•mean cell/corpuscular hemoglobin (MCH)
• mean cell/corpuscular hemoglobin concentration (MCHC)

17
Q

What is the diagnostic use of the three RBC indices? 

A

Used in classifying and differentiating anemia‘s

18
Q

What is the normal MCV value?

A

80-100 fL (size of cell)

Above is macrocytic, below is microcytic, and normal is normocytic

19
Q

What is the formula for MCV?

A

Hematocrit (%) x 10 Divided by
RBC 

20
Q

What does MCV indicate? And what are the units

A

Average volume of a single RBC, femtoliters 

21
Q

What is the normal range for MCH? And what does it indicate?

A

26-34 pg (picograms)

Average weight of hemoglobin per RBC

22
Q

If MCH doesn’t correlate with MCV, you have ________________. 

A

Spherocytes 

23
Q

What can MCH confirm?

A

If RBCs are microcytic or macrocytic

24
Q

What does MCHC stand for?

A

Mean corpuscular hemoglobin concentration

25
Q

What is the normal MCHC range? 
And what does it measure?

A

31-37 g/dL

Average concentration of hemoglobin in each RBC

26
Q

What is the formula for MCH?

A

Hemoglobin x 10. Divided by
RBC

27
Q

What is the formula for MCHC?

A

Hemoglobin / by hematocrit (%)

X100

28
Q

What is the term for increased and Decreased MCHC?

A

Spherocytes (above 37)
Hypochromic

Normochromic

29
Q

An MCHC value of 33 g/dL Is the same as….

A

33%

They are equivalent units

30
Q

Hyperchromic RBCs are actually caused by a shape changed, and thus are only found in….

A

Scherocytes 

31
Q

Why should any MCHC value over 37 g/dL The recalculated?

A

Because normal RBCs can’t hold more Hgb than 37 g/dL

A result of over 37 would mean scherocytes are present 

32
Q

True or false,
hyperchromic is used as a description of erythrocyte morphology 

A

False

33
Q

Elevated MCHC is most likely due to…

A

Error 

34
Q

What is the normal RBC adult range?

A

4.0- 6.0 x10^12L

35
Q

What is the normal hemoglobin adult range?

A

12.0-18.0 g/dL

36
Q

What is the normal adult hematocrit range?

A

36-53%

37
Q

Is every RBC that lacks a zone of pallor a spherocyte?

A

No

38
Q

Term used when there’s a variety of sizes of the RBC‘s

A

Aniosocytosis

39
Q

Term used when there is decrease in hemoglobin for an increase in pallor

A

Hypochromic

Hematology Lab (13 decks)

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