Microevolution Flashcards
Microevolution?
Focus on evolutionary change in a population by changes in the allele frequencies that affects the genetic composition of populations.
Forces?
Natural selection
Genetic drift
Gene flow
The result?
A phenotype is the product of an inherited genotype and the environmental influences
Mutations and heterozygote protection?
A harmful mutation can be hidden from selection and a recessive allele can be masked by heterozygote protection and there may be a pool of alleles that may not be favoured under present conditions but can shown if the environment changes.
Key point?
Only mutations in cell lines that produces gametes can be passed to offspring
Key potential sources of variations?
Translocation
Errors in meiosis - unequal crossover
Slippage during DNA replication
Transposable elements
Gene duplications that do not have severe effects can persist over generations and provide an accumulation of mutations = expanded genome.
Sexual reproduction?
Homologous chromosomes 1 from each parent trade alleles by crossing over
Which are then distributed randomly into gametes
Fertilization typically brings together gametes that have different genetic background
Gene pool?
A population genetic make up of all copies of every type of allele @ every locus in all members in the population
Hardy-Weinberg?
In a population that is not evolving the allele and genotype frequencies will remain constant from generation to generation.
Only segregation and recombinations of alleles.
To asses if natural selection or other forces are causing evolution @ a particular locus, by determining what the genetic make up of a population would be if it were not evolving
Gene duplication?
Where a similar gene gets copied and added to the same chromosome and can have different outcomes:
It can be inactivated
It can provide more gene product
It can specialize in another function, keeping the same function for the similar gene - neofunctionalisation or subfunctionalisation. Resulting in paralogs or orthologs.
Allele frequency?
p and q and alleles can be either homo or heterozygous giving the equation:
p^2+2pq+q^2=1
Key point Hardy-Weinberg?
Population is in eq only if the observed genotype frequencies are equal to one, indicated a non-evolving population
Hardys big 5?
No mutations - gene pools cannot be modified
Big population - smaller are greater affected
No geneflow - no moving of alleles
Random mating - It describes an ideal situation in which all individuals on one sex are equally potential partners of all members of the opposite sex.
No natural selection - no difference in viability and fertility
Natural selection?
Different succes in survival and reproduction and if some are better suited to their local environment will produce more offspring. By consistently favouring some alleles leading to adaptive evolution = trait that increases survival and reproduction tend to increase over time.
Genetic drift?
Chance events that causes allele frequencies to change rapidly from 1 generation to next.
Founder effect - If few individuals become isolated can produce a gene pool that differs from the source population
Bottleneck - A sudden change in environment that drastically reduce the size of a population. By chance certain alleles may be overrepresented among survivors.