Meiosis Flashcards
Chromosome?
A single long DNA molecule and have 100 or 1000 of genes with a sequence of nucleotides along the DNA molecule.
Location on a gene = locus.
22 autosomes and 1 sex
23 maternal and 23 paternal
Homologs?
Individual chromosomes from each parent that look alike but have different versions - allele- of genes at the corresponding loci.
Prophase 1 ?
Chromosomes have been duplicated and the sister chromatids are held together by cohesins.
Duplicated homologs pair up - synapsis- and crossing over occurs, by a synaptomental complex and becomes visible as chiasmata.
Segments are transfered between non-sister chromatids - a paternal is traded for a maternal part.
Metaphase 1?
Pairs of homologs are positioned at the metaphase plate
Anaphase 1?
Duplicated chromosomes of each homologs pair move to the poles, the sister chromatid remains attached by cohesin.
Independent assortment?
Since the pair of homologs are positioned independently of the other pairs at metaphase 1, the first division results in each pair sorting its M and P homologs into daughter cells independently of every other pair.
N=23?
Combination of P and M is 2^23 - 8.4 million possible combinations of chromosomes without crossing over.
Crossing over?
Recombinant chromosomes that results in chromosomes with new combos of M and P alleles.
Metaphase 2?
Combining DNA inherited from 2 parents into a single chromosome. Different possible arrangements of non-identical sister chromatids during this phase - increases the the number of genetic types of daughter cells that can result from meiosis.
Random fertilization?
2^23 x 2^23 - 2n zygote
Mutations?
Are the original source of different alleles