Microbiome Flashcards
Name Gram+ examples of mutualistic relationships
Firmicules:
Clostridium spp.
Enterococcus spp.
Lactobacillus spp.
Name Gram- examples of mutualistic relationships
Bacteriodese
Whats the contribution of SCFA(short chain fatty acids) to the microbiome?
-energy source used by host
-synthesize vitamin B & K
-metabolises bile acids
-influences host immunity
colonisation induces a spectrum of intestinal + metabolic changes which include?
-promote the digestion & absorption of nutrients
-accelerate gut epithelial renewal
-alter epithelial locomoter activity
what is the components of the gut?
bacteria, archae & eukarya+their viruses
What does the stomach & duodenum composition contain?
10-10^2 CFU/mL- lactobacilli, streptococci, yeasts.
bacteria in the jejunum & ileum?
10^4-10^6 CFU/mL- lactobacilli, streptococci, coliform bacteria, bacteriodes,bifidobacteria, fusobacteria
whats the colon bacterial contents?
bacteriodes,streptococci,eubacteria,fusobacteria,clostridia,veilonella,coliform,labtobacilli, proteus,staphylococci,psuedomonas,yeasts and protzea
diet,stress,pharmaceuticals,geography,infant feeding and birthing process is all factors which impact what?
gut microbiome
How to acquire resident flora?
1-delivery (vaginal+c-section birth)
2-feeding (intestines diff from bottle/breast)
what is meconium?
infants earliest stool
what is meconium composed of?
intestinal epithelilal cells, mucus,amniotic fluid,bile and water.
whats the most common cause of antibiotic associated diarrhoea?
dysbiosis & C.difficile (CDAC)
symptoms of dysbiosis
mild diarrhoea to relapsing severe diarrhoea
what C.difficile symptoms affects babies and children?
pseudomonas colitis and toxic megacolon can develop
