Microbiology in the Hematopoietic System - Skildum

Question 1

What virus is in the Reoviridae family, has a dsRNA segmented genome, is not enveloped, has an icosahedral capsid, and infects proerythroblasts to mature RBCs?

Answer 1

Colorado Tick Fever Virus (CTFV)

Question 2

What virus is in the Herpesviridae (beta) family, has dsDNA genome, is enveloped, has icosahedral capsid, and infects monocytes to macrophages systemically in active infection but goes latent in CD34⁺ cells?

Answer 2

Cytomegalovirus

(CMV/HHV-5)

Question 3

What virus is in the Herpesviridae (beta) family, has dsDNA genome, is enveloped, has icosahedral capsid, and infects CD4⁺ T-cells, PBMNCs, and epithelial cells?

Answer 3

HHV-6 & HHV-7

Question 4

What virus is in the Herpesviridae (gamma) family, has dsDNA, is enveloped, has icosahedral capsid, and infects epithelial cells of the oropharynx (lytic life cycle) in acute infection but B-cells in latent infection?

Answer 4

Epstein Barr Virus

(EBV/HHV-4)

Question 5

What virus is in the Herpesviridae (gamma) family, has dsDNA genome, is enveloped, has icosahedral capsid, and infects epithelial cells and B-cells?

Answer 5

Kaposi sarcoma herpes virus

(KSHV/HHV-8)

Question 6

What virus is in the Parvoviridae family, has a +/-ssDNA genome, is not enveloped, has icosahedral capsid, and infects erythroid progenitor cells?

Answer 6

Parvovirus B19

Question 7

What virus is in the Retroviridae family, has a +ssRNA genome, is enveloped, has icosahedral capsid, and infects T-cells?

Answer 7

Human T lymphotrophic virus - 1 & 2

(HTLV-1: CD4+ & HTLV-2: CD8+)

Question 8

What virus is in the Retroviridae family, has a +ssRNA genome, is enveloped, has an icosahedral capsid, and infects CD4⁺ T-cells?

Answer 8

Human immunodeficiency virus - 1

(HIV-1, related: HIV-2)

Question 9

What virus is in the Filoviridae family, has a -ssRNA genome, is enveloped, has a helical/complex capsid, and infects Macrophages?

Answer 9

Ebola virus

(EBOV)