Microbiology GI parasites Flashcards
protozoa fall into what type of group
single celled eukaryotic
metazoa fall into what type of group
multicelluar
what is the protective measure for a protozoa
cyst form
protozoans that do not have cysts have what mode of transmission
arthropod vector
how do protozoa evade the immune system
via surface antigen variation
parasite that causes amebiasis
entamoeba histolytic
is a pseudopod forming protozoan
entamoeba histolytic
pathogenesis of E. histolytica
induces apoptosis causing blood diarrhea and also can have extraintestinal abscesses in the liver, lungs, etc). the gastric acid stimulates excystation and necrosis from cytotoxin
Entamoeba histolytic is associated with _______in the United States
camping
mode of transmission for entamoeba histolytic
fecal oral (carrier state, cysts are passed in the stool)
who are the at risk groups for E histolytic
travelers to endemic area (camping/hiking) immigrants, MSM, IC pts, institutionalized patients
diagnostic stage
trophozoite and cyst in feces
flask shape ulcers
E histolytica
two diseases caused by E. histolytica
amebic colitis and amebic liver abscess
PMN’s present in E histolytica infection ?
yes
DOC for E histolytica invasive
metronidazole
DOC for E histolytica for noninvasive
paromyocin
pig reservoir
Balantidium coli
outbreaks in US psychiatric hospitals
B coli
DOC for B coli
tetracycline
causes giardia
giardia lamblia
reservoir for giardia lamblia
beavers and muskrats are reservoirs (streams and lakes)
mode of transmission for giarddia
fecal oral from poor sanitation or contaminated drinking water; little person to person transmission
who are at risk for giardia lamblia
travelers, children in day care centers, institutionalized, and homosexual men
flagellated pear shaped body
Giardia lamblia
pathogenesis of Giardia lamblia
infective stage
excyst in duodenum
multiplies by longutudinal binary fission–trophozoites on mucosa of duodenum
bilobed nucleus
giardia lamblia
malabsorption syndrome #1 cause
giardia
diarrhea of Giardia
watery diarrhea, foul smelling, stools are NOT bloody or contain pus
falling leaf motility
giardia
treatment for giardia
metronidazole
how do you prevent giardia
boil water and treat carriers (cysts can survive in chlorinated water)
cryptosporodiosis or crypto is caused by most offten
C parvum
what is the infectious form for crypto
oocyst
resistant to chlorination
crypto parvum and giardia
what age group is affected by C parvum
mainly children about 5 years of age
what disease is supposed to be lethal in AIDS patients
C parvum
What does C parvum infect
infects the intestinal epithelial cells
Diagnosis of C parvum
acid fast staining of stool
bouts of diarrhea, greater than 50 per day in AIDs pts
C parvum
what is the treatment for C parvum
replace fluids, electrolytes and give nitazoxanide for immunocompetent pts.
malabsorption syndrome in AIDS pts
Cystoisopora belli
reservoir for cystoisospora belli
humans
mode of transmission for cystoisospora
fecal oral transmission
diagnosis of C belli
iodine stained stool smears (oocysts found in feces, stain acid fast)
what is DOC for C belli
TMP-SMX
oval oocysts
C belli
round oocysts
Crypto
AIDS, malabsorption, and acid fast
C belli
rasperies from guatemala/ basil from mexico
cyclospora cayetanesis
flouresces blue under UV light
C cayetanesis
microsporidia
Obligate intracellular spore-forming protozoa
all parasites that are not protozoa are called
metazoa
trematodes are
flukes
cestodes are
tapeworms
nematodes are
roundworms
__________ingest host tissue and or fluids
helminths
what are the protective layers of helminths
tough external layer (cuticle), immune evasion (antigenic variation and secrete enzymes that destroy host cells