Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Gastroenterology > AntiHelminths > Flashcards

AntiHelminths Flashcards

1
Q

what is the treatment of choice for all schistosome species

A

praziquantel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

katayama fever

A

systemic hypersensitivity reaction against the migrating parasites which occurs between two to eight weeks after exposure usually treated with corticosteroids or supportive care

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

albendazole, mebendazole and ivermectin are contraindicated in what pt. population

A

pregnant patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

DOC for taenia solium and neurocysticercosis

A

albendazole or praziquantel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

DOC for diphyllobothrium latum

A

niclosamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

DOC for schistosoma

A

praziquantel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

DOC for clonorchis sinensis

A

praziquantel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

only round worm that is not treated with mebendazole

A

strongyloides stercolis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

DOC for strongyloides stercolis

A

ivermectin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

DOC for ascaris lumbricoides, enterobius vermicularis, trichuris trichiura,

A

mebendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

DOC for necator americanus

A

mebendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

DOC for onchocerca volvulus

A

ivermectin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

DOC for wuchereria bancrofti and brugi malayi

A

diethlcarbazine and albendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

DOC for toxocara canis

A

tiabendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

DOC for trichenella spiralis

A

thiabendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

how is wuchereria bancrofti transmitted

A

female mosquito (anopheles or culex)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

causes filarisis

A

wuchereria bancrofti and onchocerca volvulus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

onchocerca volvulus causes

A

river blindness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

onchocerca volvulus (river blindness) is transmitted by

A

black fly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

DOC for onchocerca volvulus

A

ivermectin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

cestodes are

A

tapeworms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

trematodes are

A

flukes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

nematodes are

A

roundworms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what are the two tapeworms he wants us to know

A

taenia solium and diphyllobothrium latum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
what are the two flukes he wants us to know
schistosoma and clonorchis sinensis
26
MOA of benzimidazoles
bind to free beta tubulin and thus inhibit the polyermization of tubulin and microtubule dependent glucose uptake
27
what is the MOA of albendazole
Selective degeneration of cytoplasmic microtubules in intestinal and tegmental cells of intestinal helminths and larvae; glycogen is depleted, glucose uptake and cholinesterase secretion are impaired, and secretory substances accumulate intracellulary. ATP production decreases causing energy depletion, immobilization, and worm death
28
what is albendazole used to treat
treatment of neurocysticercosis caused by T. solium and hydatid disease of the liver, lung, and peritoneum caused by echinococcus granulosus
29
what should you do when you administer albendazole
add an anticonvulsant and steroid therapy during the first week of treatment
30
what are the adverse reactions for albendazole ?
Dizziness, vertigo, fever, intracranial pressure increase, meningeal signs, and seizures
31
Mebendazole is used for
treatment of 1) enterobius vermicularis 2) trichuris trichuria 3) ascaris lumbricoides 4) hookworms (ancylostoma duodenale)
32
what are the contraindications for mebendazole (vermox)
pregnancy (embryotoxic and teratogenic) | steven johnson syndrome
33
what is the MOA of thiabendazole
inhibits helminth specific mitochondria fumarate reductase
34
thiabendazole is DOC for
cutaneous larva migrans, trichinosis, and mixed helminthic infections
35
what is the association of fruit juice and thiabendazole
drinking fruit juice aids in the expulsion of worms by removing the mucous to which the intestinal tapeworm attach themselves
36
what are the adverse reactions for thiabendazole
angioedema, pruritis, rash, steven's johnson syndrome
37
ivermectin is DOC for
onchocerca volvulus and for strongyloidiasis
38
what is onchocerciasis
river blindness
39
what is the MOA of ivermectin
glutamate gated chloride ion channels which occur in invertebrate nerve and muscle cells (does NOT cross BBB)
40
major contraindication of ivermectin
contraindicated in menigitis pts because they have increased permeability and get neurologic side effects such as CNS depression and ataxia
41
adverse reactions to ivermectin
dizziness, encephalopathy, headache, hyperthermia, insomnia, somnolence, and vertigo
42
manzzotti reaction occurs with which drug
ivermectin and diethylcarbmazine
43
what is manzzotti reaction
arthralgia, edema, fever, lyphadenopathy, ocualar damage, pruritus, rash and synovitis
44
diethycarbamazine is DOC for
lyphatic filariasis (bancrofti and brugia malayi)
45
pyrantel pamoate MOA
causes the release of acetylcholine and inhibits cholinesterase and acts as a depolarizing neuromuscular blocker, paralyzing the helminths
46
what is pyrantel pamoate used for
pin worm, whip worm, and round worm
47
MOA of praziquantel
Increases the cell permeability to calcium in schistosomes, causing strong contractions and paralysis of worm musculature leading to detachment of suckers from the blood vessel walls and to dislodgment
48
use of praziquantel
schistosomiasis,
49
adverse reactions in praziquantel
CSF reaction syndrome in patients being treated for neurocysticercosis (HA, seizures, meningimus)`
50
OA of niclosamide
inhibits mitochondrial anaerobic phosphorylationof ADP in tape worms
51
what is DOC for tapeworms
niclosamide
52
hyatid disease caused by
echinococcus granulosus
53
hook worms species names
N aemricanus
54
how are hookworms transmitted
direct skin contact with free living soil larvae (walking barefoot)
55
what is the treatment for hookworms
mebendazole
56
treatment for ascaris lumbricoides
mebendazole
57
species name for pin worm
enterobius vermicularis
58
mode of transmission for pin worm
ingestion of eggs from fingers contaminated by scratching or through contact with contaminated linens or clothening
59
DOC for pinworm
enterobius vermicularis
60
DOC for whipworm
mebendazole
61
visceral larva migrans can cause
granulmatous nodules
62
what is the treatment for visceral larva migrans and cutaneous larva migrans
thiabendazole
63
ancylostoma braziliense
dog or cat hookworms that which humans are accidental host

Gastroenterology (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions