Microbiology Flashcards
how is herpes simplex virus spread
via saliva
which type of HSV is acquired in childhood
HSV type 1
how does HSV1 manifest in the mouth
gingivostomatitis - ulcers around lips, buccal mucosa and hard palate
how does reactivated HSV present
cold sores
what is carried out to confirm HSV infection
swab of lesion, transport in virus transport medium then sent for PCR
which two conditions presenting in the mouth are caused by coxsackie virus
herpangina
hand, foot and mouth disease
what is the causative organism in syphilis
bacterium - treponema pallidum
what is the treatment for syphilis
intra-muscular penicillin
what are the most common bacterial causes of sore throat
strep infection, haemophilus influenza
what is most likely cause of sore throat in person aged 15-25 if symptoms last more than two weeks
Epstein-Barr virus, infectious mononucleosis
what is the most common cause of bacterial sore throat
strep. pyogenes - usually causing follicular tonsillitis
list two complications of strep pyogenes throat infection
rheumatic fever, 3 weeks after sore throat + fever + arthritis
glomerulonephritis, 1-3 weeks after, haematuria, albuminuria and oedema
what organism causes diphtheria infection
corynebacterium diphtheriae
how does diphtheria present
very sore throat, white/grey membranous lesions across pharynx
produces endotoxin which is cardio and neurotoxic
what are the complications of glandular fever
anaemia
splenic rupture
upper airway obstruction
increased risk of lymphoma