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MSK > Microbiology > Flashcards

Microbiology Flashcards

1
Q

Bacterial capsule

A

S. Aureus virulent factor

  1. Inhibits chemotaxis and phagocytosis
  2. Inhibits proliferation of mononuclear cells
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2
Q

Slime layer

A

S. Aureus virulent factor

1. Adherence to foreign bodies

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3
Q

Peptidoglycan

A

S. Aureus virulent factor

1. Osmotic stability

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4
Q

Teichoic acid

A

S. Aureus virulent factor

1. Binds firbronectin - anticoagulant

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5
Q

Protein A

A

S. Aureus virulent factor

1. Inhibits antibody mediated clearance

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6
Q

Coagulase

A

S. Aureus virulent factor

1. Converts fibrinogen to fibrin

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7
Q

Hyaluronidase

A

S. Aureus virulent factor

1. Hydrolyzes hyaluronic acids in connectective tissue

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8
Q

Fibrinolysin

A

S. Aureus virulent factor

1. Dissolves fibrin clots

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9
Q

Lipases

A

S. Aureus virulent factor

1. Hydrolyze lipids

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10
Q

Nucleases

A

S. Aureus virulent factor

1. Hydrolyze DNA

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11
Q

Cytotoxins

A

Don’t kill specific cells

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12
Q

Exfoliating toxins

A

Scalded skin syndrome

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13
Q

Superantigens

A

Cause massive expansion of T cells -> attack host

1. Cytokine storm

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MSK (13 decks)

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