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PLE > MICROBIOLOGY > Flashcards

MICROBIOLOGY Flashcards

1
Q

VIRULENCE FACTOR OF STAPH AUREUS

A

PROTEIN A

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2
Q

MOST COMMON CAUSE OF ACUTE ENDOCARDITIS

A

STAPH AUREUS

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3
Q

LEVEL OF EPIDERMIS, DERMIS AFFECTATION OF SSSS

A

STRATUM GRANULOSUM

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4
Q

PANTON VALENTIN LEUKOCIDIN , ASSOCIATED WITH WHAT BACTERIA

A

STAPH AUREUS

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5
Q

BACTERIA WHICH IS NOVOBIOCIN SENSITIVE

A

S. EPIDERMIDIS

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6
Q

Most common cause of prosthetic valve endocarditis

A

staph epidermidis

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7
Q

organism who has exotoxin B as virulence factor

A

strep pyogenes

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8
Q

PYR test detects what organism

A

pyogenes, group D

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9
Q

hippurate hydroylysis test

A

strep agalactiae

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10
Q

bile and optochin resistant

bile and optochin sensitive

A

resistant: group D

sensitive pneumonia

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11
Q

bacteria associated with colon cancer

A

streptococcus bovis

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12
Q

marantic endocarditis

A

streptococcus bovis

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13
Q

major virulence factor of strep pneumo

A

polysaccharide capsule

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14
Q

virulence factor for viridans strep

A

glycocalyx

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15
Q

most common cause of subacute bacterial endocarditis

A

viridans strep, strep sanguis

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16
Q

virulence factor of bacillus anthracis, specific

A

protein capsule, poly D glutamic Acid

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17
Q

bacteria that causes massive mediastinal hemorrhage

A

anthrax

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18
Q

enumerate toxins of bacillus anthracis

A

edema toxin
protective antigen
lethal toxin

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19
Q

box car shaped rods

A

bacillus anthracis

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20
Q

colony characteristic of bacillus anthracis

A

medusa head

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21
Q

heat stable enterotoxin

heat labile enterotoxin

A

stable-staph aureus

labile- bacillus cereus

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22
Q

mechanism of action of tetanospasmin

A

inhibits the release of GABA and glycine

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23
Q

DOC cutaneous anthrax

A

ciprofloxacin

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24
Q

virulence factor of clostridium tetani

A

flagella

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25
Q

virulence factor of clostridium botulinum

A

flagella

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26
Q

MOA of botox toxin

A

inhibits release of ach from peripheral nerves

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27
Q

DOC for botulism

A

botulinum antitoxin

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28
Q

toxin of clostridium perfringens

A

lecithinase aka alpha toxin

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29
Q

culture medium and colony characteristic of clostridium perfringens

A

egg yolk , double zone of hemolysis

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30
Q

antibiotics associated with pseudomembranous colitis

A

clindamycin, ampicillin, second and third generation cephalosporins

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31
Q

clinical manifestation of corynebacterium dipth

A

cardiac : av conduction block

neuro: GBS and peripheral nerve palsies including GBS

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32
Q

modified elek test is for what organism

A

corynebacterium diphtheria

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33
Q

MOA of the major virulence factor of listeria monocytogenes

A

listeriolysin o, allows escape from the phagolysosome

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34
Q

predisposing factor of actinomyces infection

A

dental extraction

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35
Q

bacteria that has a unique iron extracting capability

A

neisseria meningitides

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36
Q

most common cause of meningitis among 2-18yo

A

n. meningitides

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37
Q

prophylaxis for those exposed with meningo

A

rifampin, ciproflox

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38
Q

most severe form of neisseria meningitides

A

waterhouse friedricksen disease

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39
Q

late complement components will lead to a susceptibility to this micro organism

A

neisseria

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40
Q

virulence factor of gonorrhoeae which allows cell invasion

invasion and adherence

A

outermembrane protein

opa protein

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41
Q

confers antigenic variation for neisseria

A

pili

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42
Q

most common cause of hyperacute bacterial conjuncitivitis

A

gono

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43
Q

causes epiglottitis

A

haemophilus influenzae type b

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44
Q

aka pfeiffer’s bacilus

A

haemophilus influenzae

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45
Q

virulence factor of bordatella pertussis

A

filamentous hemagglutinin

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46
Q

culture negative subacute bacterial endocarditis

A

eikenella

kingella

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47
Q

gram negative rod , lactose fermenting, urease positive ESBL

A

klebsiella

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48
Q

what grows on skirrow’s agar

A

campylobacter

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49
Q

non lactose fermenting gram negative

A

salmonella shigella pseudomonas proteus

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50
Q

DOC meningococcal meningitis

A

ceftriaxone

51
Q

DOC for close contacts of infected persons

A

rifampicin

52
Q

antibiotic included in thayer martin against fungus

A

nystatin

53
Q

antibiotic against gram negative included in thayer martin

A

colistin and trimethoprim

54
Q

treatment for gonorrhoeae

A

ceftriaxone plus doxy to cover for chlamydia

55
Q

MC cause of hyperacute bacterial conjunctivitis

A

gonorrhoeae

56
Q

satellite growth around s aureus

A

haemophilus influenzae

57
Q

most serious manifestation of hib infection

A

meningitis

58
Q

cause of acute epiglottitis

A

hib

59
Q

virulence factor of bordatella pertussis

A

filamentous hemagglutinin FHA

60
Q

virulence factor causing whooping cough

A

tracheal cytotoxin, destroys ciliated cells

61
Q

causes Turspirina

A

bordatella

62
Q

most contagious stage of whooping cough

A

catarrhal

63
Q

T/F pertussis vaccine may be given to pregnant women

A

true

64
Q

charcoal and yeast agar grows

A

legionella

65
Q

non specific flu like symptoms of pneumonia accompanied by diarrhea

A

legionella

66
Q

virulence factor of legionella

A

endotoxin

67
Q

t/f escherichia coli can cause blood diarrhea

A

true, via the shiga toxin

68
Q

gram neg bacilli that may be transmitted via FLIES

A

shigella

69
Q

which bacteria causes invasion of the M cells of the intestine

A

shigella

70
Q

DOC shigella

A

fluoroquinolones

71
Q

bacteria that grows in XLD

A

shigella

72
Q

MC cause of bacillary dysentery

A

shigella sonnei

73
Q

Mc cause of epidemic dysentery

A

EPIDEMIC , DISSEMINAted, SHigella DYSenteria, type 1

74
Q

gold standard for diagnosis of typhoid fever

A

bone marrow culture

75
Q

patient with sickle cell anemia develops osteomyelitis or any focal lesion following ingestion of contaminated foo.

A

Salmonella cholerasuis

76
Q

organism that grows in thiosulfate citrate bile salt

A

vibrio

77
Q

most common cause of BACTERIAL GASTROENTERITIS

A

Campylobacter jejuni

78
Q

bacteria that causes reiter syndrome

A

campylobacter jejuni

79
Q

gram negative bacteria who was found to be “triple positive” what bacteria is it

A

helicobacter pylori

80
Q

organism implicated in UTI among those with nephrolith

A

proteus

81
Q

most common cause of otitis externa

A

pseudomonas aeruginosa

82
Q

organism grown on cetrimide agar

A

pseudomonas

83
Q

obligate anaerobes

A

clostridium, actinomyces, bacteroides and fusobacterium

84
Q

synergistic pathogenicity bacteria

A

bacteroides fragilis

85
Q

infection with this bacteria mimics ulcerative colits

A

campylobacter jejuni

86
Q

has predilection for erythritol

A

brucella, its a sugar seen in the placenta of cattle

87
Q

organism that require cysteine

A

francisella

88
Q

DOC for francisella

A

streptomycin

89
Q

rapid antigen test for f1 detects this organism

A

yersinia pestis

90
Q

rabbit or squirrel bite

A

francisella

91
Q

dog or cat bite

A

pasteurella

92
Q

seen as buttery colonies with musty odor

A

pasteurella

93
Q

human bite

A

eikenella corrodens

94
Q

cord factor produced by what organism?

A

mycobacterium tuberculosis

95
Q

mechanism of action of chord factor

A

inhibits neutrophil migration and destroys mitochondria

96
Q

patient is ppd positive , but has no symptoms, what is tha management

A

isoniazid for nine months

97
Q

bacteria that causes crippling

A

mycobac leprae

98
Q

drug added to treat lepromatous leprosy

A

clofazimine

99
Q

tiniest free living organism capable of self replication

A

mycoplasma pneumoniae

100
Q

most common infectious cause of SJS

A

mycoplasma pneumoniae

101
Q

most common cause of atypical pneumonia

A

mycoplasma pneumoniae

102
Q

the only bacteria with sterol in their membrane

A

mycoplasma

103
Q

bacteria associated with cold agglutinin

A

mycoplasma pneumoniae

104
Q

bacteria used in weil felix reaction to test for rickettseial dse

A

proteus

105
Q

what bacteria is culture in eaton’s agent

A

mycoplasma pneumoniae

106
Q

argyll robertson pupil

A

syphilis

107
Q

most common cause of death in congenital syphilis

A

pulmonary hemorrhage

108
Q

higoumenaki , enlargment of the sternoclavicular joint

A

congenital syphilis

109
Q

most specific test for syphilis

A

FTA ABS

110
Q

has rapid antigenic changes due to programmed rearrangements

A

borrelia recurrentis

111
Q

DOC for lyme dse

A

doxycycline

112
Q

acute leptospiremic phase what specimen do u use

A

CSF and blood

113
Q

late leptospiremic phase , specimen

A

urine

114
Q

gold standard for diagnosis of leptospirosis

A

MAT

115
Q

culture media for leptospirosis

A

EMJH

116
Q

halberstaedter prowazek inclusion

A

chlamydia

117
Q

most common cause of STD

A

chlamydia

118
Q

staccato cough

A

chlamydia

119
Q

mccoy cells with cycloheximide

A

chlamydia

120
Q

bacteria associated with atherosclerosis

A

chlamydia

121
Q

drug of choice for rickettsial infections

A

doxycycline

122
Q

cat scratch disease

A

bartonella henselae

123
Q

rickettsial dse with the highest mortality

A

q fever caused by rickettsiaakari

124
Q

the only gram positive bacteria that has LPS

A

listeria monocytogenes

PLE (4 decks)

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