Microbiology

Question 1

Organisms most often identified from CSF in shunt infection

Answer 1

coagulase negative staph

Propionibacterium

Question 2

Aspergillosis

Airborne source

Answer 2

Conidia spores from decaying vegetation and soil

Question 3

Brucellosis

Answer 3

Aerosolised from carcasses of domesticity and wild animals

Question 4

Coccidiodomycosis

Answer 4

Anthroconidia from soil and dust

Question 5

Cryptococcosis

Airborne source

Answer 5

Aerosolised from bird droppings

Question 6

Histoplasmosis

Answer 6

Conidia spores from bat or bird droppings

Question 7

Kingella kingae

Gram stain
Presentation

Labs

Answer 7

Gram negative rod

SA, OME, bacteraemia, endocarditis

Children under 5
Subtle presentation

Responds to beta lactam

Question 8

Most common cause IE

Answer 8

S aureus >50%
S viridans 20%
CONS 14%
GAS, GBS, E coli, Strep pneumoniae

Question 9

HACEK group

Name
Cause

Answer 9

Haemophilus 
Actinobacillus
Cardiobacterium hominis
Eikenella
Kingella kingae

Uncommon causes of culture negative IE

Question 10

Most common organisms in culture negative IE

Answer 10

Bartonella henselae

C. Butnetii

Tropheryma whipplei

Question 11

How much blood

Child culture

Infant culture

% positive in IE

Answer 11

5-7mL

1-3mL

90%

Continuous bacteraemia so don’t need to time with fever