Fungal Flashcards
1
Q
Polyenes
Acute reactions
Longterm reaction
A
Release of cytokines IL, TNFa
Chills, fever, aches for 2-5h
Steroid can help
Nephrotixicity
Anaemia - myelosupression, reversible
CNS toxicity if intrathecal
2
Q
Azoles
Adverse effects
Echinocandins
Adverse effects
A
QT prolongation Electrolyte disturbance Exfoliative skin reaction Photosensitivity Acute pancreatitis , hepatitis Visual disturbance
GI, hypotension, flu like illness, anaemia,hepatic enzyme deranged