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MS2 Unit 4 ER > Microbiology > Flashcards

Microbiology Flashcards

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1
Q

yeast with multiple buds (Coccidioides immitis/ Histoplasma / Blastomyces dermatitis/ Paracoccidioides)

A

Paracoccidioides brasiliensis

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2
Q

Survive endocytosis and lysosomal fusion (Coccidioides immitis/ Histoplasma / Blastomyces dermatitis/ Paracoccidioides)

A

Histoplasma capsulatum

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3
Q

Endemic to the southwest CA, AZ, NM, TX

Coccidioides/ Histoplasma / Blastomyces dermatitis/ Paracoccidioides

A

Coccidioides immitis

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4
Q

Endemic to eastern North america and great lakes region (Coccidioides/ Histoplasma/ Blastomyces/ Paracoccidioides)

A

Blastomyces dermatitis

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5
Q

endemic to rural latin america (Coccidioides/ Histoplasma/ Blastomyces/ Paracoccidioides)

A

Paracoccidioides brasiliensis

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6
Q

chronic adult form can have latency of up to 30 years (Coccidioides/ Histoplasma/ Blastomyces/ Paracoccidioides)

A

Paracoccidioides brasiliensis

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7
Q

PPD may be useful if positive for this fungal infection

Coccidioides/ Histoplasma/ Blastomyces/ Paracoccidioides

A

Coccidioides immitis

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8
Q

Which is thermally dimorphic? (Coccidioides/ Histoplasma/ Blastomyces/ Paracoccidioides)

A

ALL of them!

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9
Q

immunosuppression and disseminated infection with this mycoses can lead to tongue ulcerations (Coccidioides/ Histoplasma/ Blastomyces/ Paracoccidioides)

A

Histoplasma capsulatum

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10
Q

This systemic mycosis can cause erythema nodosum or “desert bumps” (Coccidioides/ Histoplasma/ Blastomyces/ Paracoccidioides)

A

Coccidioides immitis,
the immune system is turing on the granuloma formation response
(also possible with histoplasmosis)

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11
Q

spread by bird droppings, bat guano (Coccidioides/ Histoplasma/ Blastomyces/ Paracoccidioides)

A

Histoplasma capsulatum

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12
Q

in culture, little pears growing on a branch (Coccidioides/ Histoplasma/ Blastomyces/ Paracoccidioides)

A

Blastomyces dermatitis

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13
Q

US endemic dimorphic fungi (Coccidioides/ Histoplasma/ Blastomyces/ Paracoccidioides)

A

Coccidioides immitis
Histoplasma capsulatum
Blastomyces dermatitis

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14
Q

South American + Latin American endemic dimorphic fungi (Coccidioides/ Histoplasma/ Blastomyces/ Paracoccidioides)

A

Paracoccidioides brasiliensis

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15
Q

mold in cold, yeast in heat (Coccidioides/ Histoplasma/ Blastomyces/ Paracoccidioides)

A

Histoplasma capsulatum
Blastomyces dermatitis
Paracoccidioides brasiliensis

Coccidioides is mold in cold, sphereule endospore in heat

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16
Q

Very little inflammatory response with this opportunistic fungus (Cryptococcus/ Aspergillus/ Mucor/ Fusarium)

A

Cryptococcus, C neoformans and C gattii

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17
Q

opportunistic fungus with Septate hyphae with v-shapped branches (Cryptococcus/ Aspergillus/ Mucor/ Fusarium)

A

Aspergillus fumigatus

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18
Q

produces gliotoxin virulence factor, which is immunosuppressive (Cryptococcus/ Aspergillus/ Mucor/ Fusarium)

A

Aspergillus fumigatus

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19
Q

biopsy of this fungal infections shows septate hyphae budding at acute angles (Cryptococcus/ Aspergillus/ Mucor/ Fusarium)

A

Aspergillus fumigatus

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20
Q

Rare, dangerous, death by sinus infection (Cryptococcus/ Aspergillus/ Mucor/ Fusarium)

A

Mucor (Rhizopus)

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21
Q

Biopsy shows non-septate hyphae branching at right angles (Cryptococcus/ Aspergillus/ Mucor/ Fusarium)

A

Mucor (Rhizopus)

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22
Q

Has both a yeast form and a mold form (Cryptococcus/ Aspergillus/ Mucor/ Fusarium)

A

only Fusarium! helps differentiate from Aspergillus

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23
Q

especially infects patients with uncontrolled diabetes (Cryptococcus/ Aspergillus/ Mucor/ Fusarium)

A

Mucor (Rhizopus)

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24
Q

The most important predisposition for infection with this opportunistic mycosis is HIV (Cryptococcus/ Aspergillus/ Mucor/ Fusarium)

A

Cryptococcus

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25
Q

Stain CSF of suspected infected patient with india ink (Cryptococcus/ Aspergillus/ Mucor/ Fusarium)

A

Cryptococcus

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26
Q

what component of the TB wall accounts for it being Acid-Fast?

A

Mycolic acid

27
Q

Which T-cells does the CMI use to fight TB?

A

CD+ Th-1 cells

28
Q

A granuloma full of tuberculosis is called a ________

A

tubercule

29
Q

inflammation of lymph nodes in the neck in an adult by reactivating TB is called _______

A

scrofula

30
Q

When TB infects the bones of the spine it is know as ______ disease

A

Pott’s

31
Q

A calcified TB lesion of the lung plus a hilar lymph node is called a _____ _____

A

Ghon complex

32
Q

In Lepromatous leprosy, there is a useless (Th1/ Th2) response

A

Th2

33
Q

Immunogenic nerve damage happens in (Tuberculoid/ Lepromatous) leprosy

A

Tuberculoid

34
Q

Bacterial nerve damage happens in (Tuberculoid/ Lepromatous) leprosy

A

Lepromatous

35
Q

Lepromatous skin test positive (Tuberculoid/ Lepromatous) leprosy

A

Tuberculoid, positive

Lepromatous, negative no CMI

36
Q

Leprosy is treated with ______

A

Dapsone (+ rifampin)

37
Q

produces pyocyanin with green color

P. aeruginosa/ B. cepacia/ B. pseudomallei/ B. mallei

A

Pseudomonas aeruginosa

38
Q

commonly affects patients with CF, not healthy patients

P. aeruginosa/ B. cepacia/ B. pseudomallei/ B. mallei

A

Burkholderia cepacia

39
Q

maintained in animal reservoirs abroad

P. aeruginosa/ B. cepacia/ B. pseudomallei/ B. mallei

A

Burkholderia mallei

40
Q

From contaminated water or soil, may be seen as reactivation in Vietnam vets (P. aeruginosa/ B. cepacia/ B. pseudomallei/ B. mallei)

A

Burkholderia pseudomallei

41
Q

Obligate intracellular (Pseudomonas + Burkholderia/ Chlamydia)

A

Chlamydia

42
Q

Very antibiotic resistant (Pseudomonas + Burkholderia/ Chlamydia)

A

Pseudomonas + Burkholderia

43
Q

pneumonia with history of bird handling (C. pneumoniae/ C. psittaci/ C. trachomatis)

A

C. psittaci

44
Q

community acquired pneumonia, risk at nursing homes (C. pneumoniae/ C. psittaci/ C. trachomatis)

A

C. pneumoniae

45
Q

transmitted when infant passes though birth canal (C. pneumoniae/ C. psittaci/ C. trachomatis)

A

C. trachomatis

46
Q

Legionella has a type (1/2/3/4) secretion system

A

T4SS

47
Q

Pseudomonas aeruginosa has a type (1/2/3/4) secretion system

A

T3SS

48
Q

Chlamydia has a type (1/2/3/4) secretion system

A

T3SS

49
Q

can cause both pneumonia and hepatitis (legionella/ Coxiella burnetti/ mycoplasma)

A

Coxiella burnetti

50
Q

the only bacteria without a cell wall (legionella/ Coxiella burnetti/ mycoplasma)

A

mycoplasma

51
Q

CARDS exotoxin causes ciliary stasis (legionella/ Coxiella burnetti/ mycoplasma)

A

mycoplasma

52
Q

prevents alveolar macrophages from doing phago-lysosomal fusion (legionella/ Coxiella burnetti/ mycoplasma)

A

legionella

coxiella SURVIVES endolysosomal fusion

53
Q

antibodies cross reactive with RBC’s, cold agglutinins, pt may become anemic (legionella/ Coxiella burnetti/ mycoplasma)

A

mycoplasma

54
Q

replicate in nucleus, segmented ssRNA (orthomyxovirus/ paramyxovirus)

A

orthomyxovirus

55
Q

replicate in cytoplasm, non-segmented ssRNA (orthomyxovirus/ paramyxovirus)

A

paramyxovirus

56
Q

To vaccinate against Haemophilus influenza, we target the capsule protein called ___

A

PRP, polyribosyl ribitol phosphate

for Hib

57
Q

H. influenza strain Hib is more pathogenic than the NTHi due to it’s immune evading ________

A

capsule

58
Q

which is well known for causing epiglottitis? (Hib/ C. pneumoniae/ Mucor (Rhizopus)/ B pertussis)

A

Haemophilus influenza b, Hib

59
Q

Growing Haemophilus influenza in culture requirers growth on chocolate agar with both coag factors __ and ___

A

X and V

60
Q

Which can attached to and kill the cilia of elevator in the respiratory tract (Hib/ C. pneumoniae/ Mucor (Rhizopus)/ B pertussis)

A

B pertussis

61
Q

What causes ‘whooping cough’? (Hib/ C. pneumoniae/ Mucor (Rhizopus)/ B pertussis)

A

B pertussis

62
Q

Which has a vaccine available? (H. influenza Hib/ H. influenza NTHi/ B. purtussis)

A

H. influenza Hib and B. pertussis

63
Q

Which has fillamentous haemaglutinin? (H. influenza Hib/ H. influenza NTHi/ B. purtussis)

A

B pertussis

MS2 Unit 4 ER (3 decks)

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