Microbiology Flashcards

1
Q

Symptoms

A
fever 
productive cough 
SoB 
hypoxia 
High RR 
Confusion
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2
Q

What is CAP

A

Clinical lower respiratory tract infection + new pneumonic changes on CXR + onset of symptoms in the community or within 48 hours of hospital admission

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3
Q

What increases chances of CAP

A

COPD
Diabetes
CV disease
Immunosuppression

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4
Q

what is seen in CAP

A

peak age 50-70

Seasonal- winter and early spring

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5
Q

COmmon causes of CAP

A

Streptococcus pneumoniae – most common
Haemophilus influenzae

Moraxella catarrhalis
Staphylococcus aureus/MRSA – common after a viral pneumonia as a secondary bacterial infection
Group A streptococcus species

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6
Q

Atypical causes of CAP

A

Mycoplasma pneumonia
Legionella
Chlamydia

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7
Q

Investigations if suspect pneumonia

A
CXR
Bloods- FBC/U&E/CRP/LFT
Blood cultures
Sputum sample 
Urinary antigens (if suspect atypical cause)
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8
Q

How to decide how sever pneumonia is

A

CURB 65 (new onset confusion, urea>7, RR>20, BP <90/60, Age>65

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9
Q

What does the CURB 65 score help you decide

A

Where to manage

Antibiotic choice

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10
Q

Hospital acquired pneumonia definition

A

Clinical lower respiratory tract infection + new pneumonic changes on CXR + onset of symptoms > 48 hours after admission OR admission in the last 7 days

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11
Q

Risk factors for HAP

A

Age >70, severe underlying disease, poor mobility

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12
Q

Common organisms HAP

A

Enteric gram negative bacilli- includes enterobacteriacia and pseudomonas species

Strep pneumoniae
Haemophilus influenza
Staphylococcus aureus

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13
Q

Is there HAP severity guidelines

A

No. Only CAP

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14
Q

What is HAP severity dependent on

A
Clinical decision
-New confusion
-High respiratory rate
Hypoxia
Severity of CXR (bilateral or multilobular)
HYpotension
-Need for ventilatory support
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15
Q

What is aspiration pneumonia

  • Does it show on CXR
  • When to suspect
  • What to do If suspected
A

Aspiration of gastric contents leading to chemical inflammation and infection

  • Does not always show on CXR.
  • Suspect who has a low GCS and evidence of vomiting
  • Add metronidazole for HAP or CAP
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16
Q

evidence of sepsis

A

Evidence of organ dysfunction: AKI, new confusion, hypoxic and high RR, deranged clotting, deranged LFT

17
Q

What is septic shock

A

Sepsis plus
- Refractory hypotension (still hypotensive despite adequate IV fluids) requiring vasopressors (drugs to increase blood pressure)
AND
- Raised lactate

18
Q

Complications of pneumonia

A

Sepsis
Lung abscess
Empyema

19
Q

What is a lung abscess and when is it seen

A

Pus fulled collection in lung parenchyma (seen especially in staph aureus pneumonia)

20
Q

What is empyema

-When is it seen

A

Pus filled collection in the pleural space (CXR)

  • Often develops from a parapneumonic (next to pneumonia) effusion
  • Seen especially in Streptococcus pneumonia
21
Q

When can lung abscesses and empyemas be suspected

A

Persistent swinging pyrexia and rising CRP despite treatment