Microbiology Flashcards

1
Q

What cancers does Epstein-Barr virus cause?

A

1) Burkitt’s lymphoma
2) Hodgkin’s lymphoma
3) Post transplant lymphoma
4) Nasopharyngeal carcinoma

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2
Q

What cancers does HPV 16/18 cause?

A

1) Cervical cancer
2) Anal cancer
3) Penile cancer
4) Vulval cancer
5) Oropharyneal cancer

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3
Q

What cancer does HHV 8 cause?

A

Kaposi’s sarcoma

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4
Q

What cancer does Hep B/C cause?

A

Hepatocellular carcinoma

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5
Q

What cancers does Human T-lymphotropic virus 1 cause?

A

1) Tropical spastic paraparesis

2) Adult T cell leukaemia

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6
Q

What cancers does HIV cause?

A

1) Kaposi’s sarcoma
2) Invasive cervical cancer
3) B-cell non-Hodgkins lymphoma
4) Burkitt’s Lymphoma

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7
Q

What are the different antibiotic classes in terms of mechanism of action?

A

1) Cell wall synthesis
2) Nucleic acid synthesis
3) Protein synthesis
4) Alteration of cell membrane
5) Antimetabolite activity

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8
Q

Name the different types of abx that affect bacterial cell wall synthesis

A

1) Beta lactams
- Penicillins
- Cephalosporins
- Carbapenams
- Monobactams

2) Vancomycin
3) Bacitracin

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9
Q

Name the different types of abx that affect bacterial nucleic acid synthesis

A

1) Folate synthesis
- Sulphonamides
- Trimethoprim

2) DNA gyrase
- Quinolones
- Metronidazole

3) RNA Polymerase
- Rifampicin

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10
Q

Name the different types of abx that affect bacterial protein synthesis

A

1) 50S subunit
- Macrolides
- Clindamycin
- Linezolid
- Chloramphenicol
- Streptograms

2) 30S subunit
- Tetracyclines
- Aminoglycosides

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