Microbial Regulatory Systems

Question 1

what is quorum sensing

Question 2

roles and advantages in cell-cell communication and coordination of cellular activities through quorum sensing

Question 3

what is an auto inducer

Question 4

quorum quenching and it’s benefits

Question 5

clinical drawbacks of quorums sensing

Question 6

MreB

Question 7

FtsZ

Question 8

Crescentin

Question 9

FilP

Question 10

Cell polarity (one asymmetric and one symmetric example)

Question 11

-ve vs + gene regulation

Question 12

stringent response

Question 13

regulon

Answer 13

collection of coregulated operons

Question 14

stress response

Answer 14

response –> activation genes in response to unfavourable environment

Question 15

Sigma factors

Answer 15

principle -> housekeeping: responsible for directing RNA pol to genes that are always expressed

alternative direct RNA pol to transcribe other genes depending on the sigma factor

anti-sigma –> binds to sigma factor will unbind and bind to phyr to from active phyr, the sigma facto can then bind to holoenzyme and direct transcription of stress genes

Question 16

two - component systems

Answer 16

based on phosphorylation
sensor kinase and response regulator