Microbial Disease Flashcards
Staphylococcus aureus
Disease: scalded skin syndrome, impetigo
VF: Alpha toxin, TSST, Exfoliant toxins A&B, and Protein A
Streptococcus pyogenes
Disease: necrotizing fasciitis, cellulitis, rheumatic fever, and pharyngitis
VF: M protein
Bordetella pertussis
Disease: whooping cough
VF: binding and paralyzes ciliated lung cells
Streptococcus pneumoniae
Disease: pneumonia and meningitis
VF: capsule
Mycobacterium tuberculosis
Disease: tuberculosis
VF: Multi drug resistance, mycolic acids, acid fast waxy surface, and difficult for ABX to penetrate
Escherichia coli
Disease: gastroentritis, UTIs, and hemolytic uremic syndrome
VF: shiga toxin
Helicobacter pylori
Disease: stomach ulcers and gastric cancer
VF: urease positive and flagella
Treponema pallidum
Disease: syphilis
VF: motility
Neisseria gonorrhoeae
Disease: gonorrhea
VF: binds to CD4+ T cells and inhibits T cell activation
Neisseria meningitidis
Disease: meningitis
VF: capsule and twitching motility (TYPE 4 PILI)
Chlamydia spp.
Disease: Chlamydia of genitals/eyes, pneumonia
VF: obligate intracellular pathogen
P. falciparum
Disease: Malaria (cerebral)
VF: chloroquine resistance is common
Yersinia pestis
Disease: Bubonic plague
VF: capsule and T3SS of toxin effectors
Borrelia burgdorferi
Disease: Lyme Disease
VF: travel to any part of the body by switching its surface antigens in the host
Normal biota of GI tract
C.difficile, E.coli, and Bifidobacterium
Main method of treating GI tract infections
restoration of microbiota by probiotics containing mostly bifidobacterium and lactobacillus
causative agent of AIDS
HIV: a lentiviral retrovirus attacks CD4+ T cells
Stages of AIDS
1st: AIDS related complex with fever, headache, and rash
2nd: AIDS with depletion of T cells and opportunistic infections
3rd: AIDS related dementia
4th: rare cancers
Endocarditis
inflammation of the heart’s inner lining (S. mutans)
Septicemia
presence of microbes in the blood
