Microbial Disease

Question 1

Staphylococcus aureus

Answer 1

Disease: scalded skin syndrome, impetigo
VF: Alpha toxin, TSST, Exfoliant toxins A&B, and Protein A

Question 2

Streptococcus pyogenes

Answer 2

Disease: necrotizing fasciitis, cellulitis, rheumatic fever, and pharyngitis
VF: M protein

Question 3

Bordetella pertussis

Answer 3

Disease: whooping cough
VF: binding and paralyzes ciliated lung cells

Question 4

Streptococcus pneumoniae

Answer 4

Disease: pneumonia and meningitis
VF: capsule

Question 5

Mycobacterium tuberculosis

Answer 5

Disease: tuberculosis
VF: Multi drug resistance, mycolic acids, acid fast waxy surface, and difficult for ABX to penetrate

Question 6

Escherichia coli

Answer 6

Disease: gastroentritis, UTIs, and hemolytic uremic syndrome
VF: shiga toxin

Question 7

Helicobacter pylori

Answer 7

Disease: stomach ulcers and gastric cancer
VF: urease positive and flagella

Question 8

Treponema pallidum

Answer 8

Disease: syphilis
VF: motility

Question 9

Neisseria gonorrhoeae

Answer 9

Disease: gonorrhea
VF: binds to CD4+ T cells and inhibits T cell activation

Question 10

Neisseria meningitidis

Answer 10

Disease: meningitis
VF: capsule and twitching motility (TYPE 4 PILI)

Question 11

Chlamydia spp.

Answer 11

Disease: Chlamydia of genitals/eyes, pneumonia
VF: obligate intracellular pathogen

Question 12

P. falciparum

Answer 12

Disease: Malaria (cerebral)
VF: chloroquine resistance is common

Question 13

Yersinia pestis

Answer 13

Disease: Bubonic plague
VF: capsule and T3SS of toxin effectors

Question 14

Borrelia burgdorferi

Answer 14

Disease: Lyme Disease
VF: travel to any part of the body by switching its surface antigens in the host

Question 15

Normal biota of GI tract

Answer 15

C.difficile, E.coli, and Bifidobacterium

Question 16

Main method of treating GI tract infections

Answer 16

restoration of microbiota by probiotics containing mostly bifidobacterium and lactobacillus

Question 17

causative agent of AIDS

Answer 17

HIV: a lentiviral retrovirus attacks CD4+ T cells

Question 18

Stages of AIDS

Answer 18

1st: AIDS related complex with fever, headache, and rash
2nd: AIDS with depletion of T cells and opportunistic infections
3rd: AIDS related dementia
4th: rare cancers

Question 19

Endocarditis

Answer 19

inflammation of the heart’s inner lining (S. mutans)

Question 20

Septicemia

Answer 20

presence of microbes in the blood