microbial communities Flashcards

1
Q

how many microbial cells on earth

A

5 * 10^30

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2
Q

4 reasons for studying microbial communities

A

global biogeochemical cycles
ecological function and resistance
biotechnology and agriculture
heath and disease

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3
Q

define biome

A

the combined abiotic and biotic factors of a given environment

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4
Q

define microbiome

A

the collection of microorganisms, their genetic material and surrounding environmental conditions

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5
Q

define microbiota

A

the assemblage of microorganisms present in a defined environment

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6
Q

define metagenome

A

the collection of genomes and genes from the members of a microbiota

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7
Q

how were early community studies performed

A

culture-based methods

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8
Q

what is the main issue with culture-based methods

A

majority of microorganisms are not culturable
biased representation of community composition

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9
Q

what is the name given to a microorganism that cannot be cultured

A

VBNC
viable but nonculturable species

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10
Q

what interactions are occuring in a microbiome

A

within and between species
with surrounding environment / host

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11
Q

give some examples of things that can affect the microbiome

A

antibiotics,
alcohol,
smoking,
travel,
diet,
occupation,
stress

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12
Q

what microbiome is most affected by diet

A

gut microbiome

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13
Q

give an example of diet affecting the gut microbiome

A

travellers diarrhoea

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14
Q

what effects do microbial metabolites have on host health

A

both positive and negative

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15
Q

what happens to your microbiome at birth and how is it affected

A

influx of microbes at birth
community dependent on whether you were pre-term and delivery method (natural vs c-section)

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16
Q

what are Bifidobacterium and Lactobacillus associated with

A

good gut health

17
Q

what nerve is responsible for the effect of stress on the microbiome

A

vagus nerve which connects brain to gut

18
Q

what responses can occur as a result of stress

A

increased mucous secretion,
fight or flight (cortisol),
immune signalling,
vagus nerve action,
neurotransmitters,
neuromuscular control of peristasis

19
Q

well known symptom of vagus nerve activation

A

stomach cramps when stressed

20
Q

what can be the risks of a unhealthy gut microbiome

A

heart attack, stroke and other health complications

21
Q

give some examples of how microbiomes can be used to benefit agriculture

A

improve food security,
improve health and disease resistance,
improve feed efficiency,
better quality and more nutritious meat / milk,
reduce methane production in cows,
exploit novel (more susutainable) food sources