Microanatomy of Reproductive System Flashcards
What is the female reproductive system composed of ( Hint: 6 )
1- Ovaries 2- Fallopian tubes 3- Uterus 4- Cervix 5- Vagina 6- Placenta ( when pregnant) 7- mammary glands ( nutrition for newborn )
What are oocytes
female gametes
What is the Function of ovaries
Where oocytes are developed
What is the function of Fallopian tubes
Collects ovulated oocytes and is the site of fertilization
What is the function of the uterus
Site of decidualisation , menstruation , implantation and placenta growth
What is the function of the cervix
Neck of the uterus that provides aa barrier to infections. Dilates and secretes to regulate partition and reproduction
What is the function of the Vagina
Key deposition of sperm and protection of reproductive tract.
What happens during menopause
Reproductive system undergoes attrition , it involutes and stops functioning reproductively.
What encapsulated the ovary
Tunica Albuginea
What lines the ovaries
Single layer of germinal epithelium on the exterior of the tunica Albuginea
What is the ovary composed of and what does each section contain ( not including Tunica albuginea and epithelium )
Cortex: oocyte and follicular development
Medulla : loose CT with BV from hilum and fibroblasts
What is the function of the fibroblasts in Medulla
Sense levels of hormones in the ovary
What are the follicles in the ovary cortex
Structures that contain the oocytes.
What are primordial germ cells
Cells that gave rise to female gametes ( haploids ). When women is pregnant the developing baby will have her own germ cells move to gonads and develop to into oogonia
During the first 3-8 months of gestation what happens to primordial
Primordial germ cells develop into large primary oocytes
How many follicles are produced in utero vs at puberty
4 million but many are lost through atresia that by puberty there’s only 200K left. .
Approximately how many oocytes are ovulated for potential fertilization
450
What is follicular maturation
Changes of oocyte during monthly cycle.
What are the 4 distinguishable follicles during maturation stages in monthly cycle
1- primordial follicles
2- primary follicle
3– Secondary follicles
4– Mature graafian follicles
What follows the antra follicle stage where there is a mature graafian follicle
Oocyte will be ovulated ( leave ovary ) and collected by Fallopian tube
What is the corpus luteum
The Graafian mature follicle without the oocyte ( since it got ovulated )
What is the function of the corpus luteum if there is a pregnancy
Major endocrine regulator during first months of pregnancy until placenta develops and takes over ( 3 months ).
What happens to the corpus luteum if there is no pregnancy
Will regress and the follicular cells will undergo atrophy and become fibrotic. Structure left will be called corpus albican
Why is the corpus luteum yellow
Because there is a lot of progesterone and estrogen being produced
What are primordial follicles
Principle follicles present before birth
Consist of oocyte surrounded by single layer of follicular cells that develop into granulose cells
Explain the process of primordial follicle becoming a primary follicle
Every month 20-40 primordial follicles are stimulated to grow bigger.
Oocyte grows bigger and secrete zona pellucida and granulosa cells turn into cuboidal shape.
What is zona pellucida
a thin glycoprotein coating secreted by the oocyte once it grows and separates the oocyte from the granulose cells
How many graafin follicles are there
Only 1
Explain the process of primary follicle becoming a secondary follicle
Increase of granulosa cell layers and it becomes called zona granulosa with a basement membrane that separates granulosa cells from outer Theca cell layer
What are theca cells and list their functions
Cells that form outside the follicle. Two layers.
- theca interna : produces oestrogen and progesterone
- theca externa
What is follicular antrum and when does it happen
When the secondary follicle matures fluid forms in follicle to nourish granulosa cells
Explain the process of secondary follicle becoming a graafin follicles
Oocyte moves ecentrically.
Follicle grows as antrum enlarges.
Follicle cells form around oocyte . ( corona radiate )