Microalbuminuria and C peptide Flashcards
- one of the smallest proteins found in the circulation
Microalbuminuria
- if the permeability of the glomerulus increases, one of the first type protein excreted out of the urine is albumin
Microalbuminuria
: similar to Albuminuria
- Protenuria
- smallest protein; first to be excreted
Albumin
- increase in urinary albumin: early sign of
diabetic renal nephropathy
persistent hyperglycemia
diabetic renal nephropathy
DM is poorly controlled
diabetic renal nephropathy
renal tubules are exposed to high plasma glucose conc
diabetic renal nephropathy
Glucose presented in the renal tubules is too high
- inability to reabsorb [?] (also excreted out of the urine)
- positive for [?]
albumin
protein
- most common cause of death
renal failure
Detection: assist in early diagnosis before the development of
heavy protenuria
Kidneys excrete a large amount of protein
heavy protenuria
heavy protenuria normal value
> 0.5g/day
Diagnosis: when [?] specimen collected within [?] are abnormal
2 out of 3
6 months
- pro-insulin cleaved to give C-peptide and insulin
C peptide