Micro Final Flashcards
Why won’t using 100% alcohol work
requires 5% water due to evaporation
ANTImicrobial drugs–drug that disrupt cytoplasmic membranes of antifungals
Azoles
Miconazole
ANTImicrobial drugs–
what steroid inhibits, keeping the membrane fluid when it’s hot and stable when it’s cold
ERGOSTEROL
ANTImicrobial drugs–what drug blocks the binding site for PABA
SULFONAMIDE
ANTImicrobial drugs when PABA is blocks what mechanism is prevented
FOLIC ACID SYNTHESIS
antimicrobial drugs that disrupt cytoplasmic membranes
ANTIFUNGALS–MICONAZOLE
example of an attachment factor during infection virulence
PILI OR fimbriae
adhesions that facilitate attachment
Invasion of host by a pathogen
INFECTION
ability of a microbe to cause disease
PATHOGENICITY
5 stages of infectious disease
incubation
prodromal
illness
decline
convalescence
When a virus enters the body what releases a SIGNAL to tell other cells to protect themselves
interferon
aTTachment inhibitors
T20–targets Helper T cell
Fusion inhibitors (way of entry into cell)
RAFI’s enveloped virus
mode of transmission of infection that travels 3ft or less
DROPLET transmission
travels short distances
exhaling coughing sneezing
anything chemical that will alter your normal physiology
DRUGS
A destructive enzyme during infection invasion that destroys connective tissues
HYALURONIDASE
COLLOGENASE
Achieved through secretions ,excretions,and bodily fluids
PORTAL OF EXIT
what is key when it comes to treatment of infections
*must be more toxic to pathogen than the host
**the more differences the more targets
why are there so many antibacterial drugs
bacteria are PROKS with a CELL WALL –the cell wall is targeted by the drug because humans don’t have this
why are their fewer antifungal and antiprotozoal drugs
Because they (fungals/protozoa) are EUKS and are closer in make up to us - will harm us too
very few antiviral drugs
viruses use our cells to replicate- will harm us too
Pro: very effective
Con: fewer applications
Narrow spectrum-targets FEW pathogens
what pumps drug out before it can act
Efflux pumps (E for Exit)
What microbe is most susceptible to ALCOHOL
ENVELOPED bacteria
what microbe is susceptible to BLEACH
ENDOSPORES
What kind of surface can Ethelene Oxide Gas be used on
HEAT SENSATIVE MATERIALS like hospital bed mattress