MG Deck 1 Flashcards
Describe the structure of DNA
Double-stranded helix of nucleotides that run Antiparallel
Why is the replication of DNA considered semi-conservative
Each strand of the original molecule serves as a template. New DNA contains one conserved parental strand and one new one.
Major players of DNA replication
Helicase, Topoisomerase, Primase, Ligase and DNA Polymerase
Primase
RNA Primer-start site for the enzyme that makes DNA
Helicase
The enzyme that unzips the DNA
Topoisomerase
The enzyme that relaxes the strand for helicase to do its job
Ligase
Binds (glues) the lagging strand
DNA Polymerase
Reads DNA from 3-5 prime and synthesizes (makes) DNA from 5-3 prime.
Why do DNA strands run Antiparallel?
due to space constraints
Has linear DNA and multiple origins of replication
Eukaryotes
1 origin bubble of replication
Prokaryotes
All genetic information in a cell
Genome
Molecule of DNA plus proteins
Chromosome
Who does translation?
Ribosomes
Segment of DNA encoding a functional product -has a non coding region
Gene