MICRO 7 Flashcards
The finding of “sclerotic bodies” described as copper pennies in biopsy material is associated with which of the following fungal infections?
A. Blastomycosis
B. Chromomycosis
C. Sprorotrichosis
D. Eumycetoma
B. Chromomycosis
The most common mycotic pulmonary infection is caused by which of the following?
A. Pneumocystis spp.
B. Rhizopus spp.
C. Histoplasma capsulatum
D. Aspergillus fumigatus
C. Histoplasma capsulatum
Hortaea wernickii is the causative agent of which of the following?
A. Tinea manus
B. Madura foot
C. Black piedra
D. Chromoblastomycosis
A. Tinea manus
TRUE statements of pityriasis versicolor include which of the following?
A. The infection elicits a granulomatous inflammatory response in the skin
B. Causative agent is a dematiaceous fungi
C. Selenium sulfide is not part of the treatment protocol
D. Scrapings of the lesion is described microscopically as “spaghetti and meatball” appearance
D. Scrapings of the lesion is described microscopically as “spaghetti and meatball” appearance
The presence of spherules containing several endospores in tissue samples taken from the lung is a pathognomonic lesion of a fungal infection caused by which of the following?
A. Coccioides immitis
B. Blastomyces dermatitis
C. Paracococcioides brasilliensis
D. Histoplasmosis capsulatum
A. Coccioides immitis
All of the following disease entities are considered systemic fungal infections with the exception of
A. blastomycosis
B. mucormycosis
C. paracoccidiodomycosis
D. histoplasmosis
B. mucormycosis
Which if the following is an opportunistic mycosis characterized by a predilection of hyphal elements to invade blood vessels causing thrombosis, infarction, and massive tissue necrosis?
A. Zygomycosis
B. Aspergillosis
C. Candidiasis
D. Cryptococcosis
A. Zygomycosis
What is the term applied to fungal infections characterized by the presence of darkly pigmented septate hyphae in tissues?
A. Phaeohyphomycosis
B. Sprorotrichosis
C. Mycetoma
D. Chromoblastomycosis
A. Phaeohyphomycosis
Desert Rheumatism:
A. Blastomycosis
B. Paracoccidioidomycosis
C. Histoplasmosis
D. Coccidioidomycosis
D. Coccidioidomycosis
San Valley fever
A. Blastomycosis
B. Paracoccidioidomycosis
C. Histoplasmosis
D. Coccidioidomycosis
D. Coccidioidomycosis
Gilchrist’s disease:
A. Blastomycosis
B. Paracoccidioidomycosis
C. Histoplasmosis
D. Coccidioidomycosis
A. Blastomycosis
South American blastomycosis:
A. Blastomycosis
B. Paracoccidioidomycosis
C. Histoplasmosis
D. Coccidioidomycosis
B. Paracoccidioidomycosis
Which of the following fungal diseases is/are caused by the so-called “black molds”?
- Chromoblastomycosis
- Phaeohyphomycosis
- Maduromycosis
- Aspergillosis
- Chromoblastomycosis
- Phaeohyphomycosis
- Maduromycosis
Which of the following statements regarding Pneumocystis jiroveci is/are correct?
- No known reservoir is demonstrated
- The cyst form is the infective stage
- It does not cause disease in the absence of immunosuppression
- Itraconazole is the drug of choice
- No known reservoir is demonstrated
- The cyst form is the infective stage
- It does not cause disease in the absence of immunosuppression
A 28-year old florist had her finger pricked while pruning rose bushes. This leads to formation of localized pustule that becomes an ulcerated lesion. Few days later, nodules began to appear in her wrist and proximal arm. Tissue biopsy would most likely reveal which of the following?
- Presence of asteroid body
- A granulomatous inflammation
- Fusiform yeast cells
- Caseous necrosis
- Presence of asteroid body
- A granulomatous inflammation
- Fusiform yeast cells
The presence of spherules containing several endospores in tissue samples taken from the lung is a pathognomonic lesion of a fungal infection caused by which of the following?
A. Coccioides immitis
B. Blastomyces dermatitis
C. Paracoccidioides brasiliensis
D. Histoplasmosis capsulatum
A. Coccioides immitis
Which of the following statements associated with cutaneous mycoses is CORRECT?
A. Zoophilic dermatophytes are easiest to identify because they produce the greatest number of conidia
B. The location of choice to obtain specimen for diagnosis is at the center of the lesion where hyphal growth is most robust
C. Lesions are somewhat worse with anthropophilic fungi as they produce the most number of irritants
D. Clinical forms are based on site of involvement
D. Clinical forms are based on site of involvement
Which of the following is an opportunistic mycosis characterized by a predilection of hyphal elements to invade blood vessels causing thrombosis, infarction, and massive tissue necrosis?
A. Zygomycosis
B. Cryptococcosis
C. Aspergillosis
D. Candidiasis
A. Zygomycosis
An impoverished 51-year old farmer was examined by a newly licensed freshly deployed doctor to the barrios. Patient exhibit swelling in his right foot with an oozing wound draining dark red to black granules. He confessed the condition developed 2 months after he step on something hard barefooted while preparing his land for the next planting season. It caused a tear on his heel which, until the time of consult, the wound has not fully healed. You sent tissues for biopsy and culture studies to a university hospital 1 hour away by car. 2 weeks later a classmate of yours in medical school working in the said medical facility sent a picture of the etiologic agent via your FB messenger without divulging the rest of the microbiologic report Which anti-fungal drug would be the best suited for his condition?
A. Ketoconazole
B. Nystatin
C. Flucytosine
D. Miconazole
A. Ketoconazole
Which of the following thermally dimorphic fungi is NOT associated with endemicity and an airborne mode of inoculation?
A. Paracoccidioides brasiliensis
B. Coccioides immitis
C. Sporothrix schenckii
D. Blastomycosis dermatitis
C. Sporothrix schenckii
A 10-year old child undergoing chemotherapy for acute leukemia began to complain about recurring headaches, stiff neck, and disorientation. CSF taken from a lumbar puncture reveal presence of encapsulated unicellular yeast cells on negative staining. The causative agent is best classified as a:
A. Deuteromycete
B. Ascomycete
C. Basidiomycete
D. Zygomycete
C. Basidiomycete
Which of the following is/are considered systemic fungal infection/s?
- Histoplasmosis
- Blastomycosis
- Paracoccidioidomycosis
- Mucormycosis
- Histoplasmosis
- Blastomycosis
- Paracoccidioidomycosis
The 4 primary systemic mycoses have the following characteristics in common:
- Infections are initiated first in the lungs
- Causative agents are dimorphic fungi
- Geographically restricted to specific areas of endemicity
- Infections are initiated first in the lungs
- Causative agents are dimorphic fungi
- Geographically restricted to specific areas of endemicity
Which of the following is not a dermatophyte
A. Microsporum
B. Trichosporum
C. Trichophyton
D. Epidermophyton
B. Trichosporum
Which is true of maduromycosis?
A. Granule color does not have relevance in determining the causative agent
B. Pathology is characterized by formation of hyaline cartilage
C. It is an occupational hazard of barefoot farm laborers
D. It does not involve deep tissues like coniguous muscles & bone
C. It is an occupational hazard of barefoot farm laborers
Which systemic mycosis is characterized by spherules containing endospores?
A. Coccidiomycosis
B. Histoplasmosis
C. Blastomycosis
D. Paracoccidiomycosis
A. Coccidiomycosis
What is the major clinical form of zygomycosis
A. Rhinocerebral
B. Periorbital
C. Thoracic
D. Cardioembolic
A. Rhinocerebral
Aflatoxin is a carcinogenic mycotoxin which causes the following carcinoma
A. Squamous cell carcinoma
B. Bronchogenic carcinoma
C. Hepatocellular carcinoma
D. Renal cell carcinoma
C. Hepatocellular carcinoma
Which of the following fungal diseases is NOT caused by the so called “black dots”?
A. Maduromycosis
B. Chromoblastomycosis
C. Aspergillosis
D. Phaeohyphomycosis
C. Aspergillosis
Presence of yeast resembling “Mariner’s Wheel” is a characteristic of which fungal infection?
A. Histoplasma capsulatum
B. Coccioides imitis
C. Blastomycosis
D. Paracoccidiodes
D. Paracoccidiodes
Which of the following is INCORRECT regarding fungi?
A. Cell wall of fungi contains sterols, while the bacteria has murein
B. Dimorphic feature is temperature dependent
C. It evokes granulomatous inflammation
D. Taxonomic classification is based on its anamorphic state
D. Taxonomic classification is based on its anamorphic state
Systemic mycoses are characterized by the following EXCEPT:
A. all are caused by a dimorphic fungus
B. all are exogenous infections
C. all are acquired by ingestion of conidia
D. all have areas of endemicity
C. all are acquired by ingestion of conidia
What is the most common disseminated form of fungal infection?
A. Mucormycosis
B. Candidiasis
C. Cryptococcosis
D. Histoplasmosis
B. Candidiasis
What is the main clinical manifestation of invasive Aspergillus?
A. Meningoencephalitis
B. Pneumonia
C. Ulcerative mucocutaneous lesion
D. Septicemia
B. Pneumonia
Pneumocystis infection is best described in humans as:
A. chronic diarrhea in debilitated
B. fungemia in AIDS and cancer px
C. pneumonia in immunocompromised
D. meningoencephalitis in elderly
C. pneumonia in immunocompromised
