Micro Flashcards
Congenital infections
TORCHS Toxo Other (HIV/Hep B) Rubella CMV HSV (VZV) Syphilis
Features of congenital infections
TORCH Thrombocytopoenia Other: Eyes/ears Rash Cerebral abnormalites (microcephaly, meningoencephalitis) Hepatosplenomegaly (Hepatitis, Jaundice)
Live Vaccines
MMR VZV Yellow Fever BCG Oral Polio (Sabin)
Inactivated vaccines
Rabies
HAV
Polio (Salk)
Conjugate vaccines
MenC
Pneumococcus
Detoxified vaccine
Tetanus
Recombinant protein vaccine
HBV
Subunit vaccines
Typhoid
Influenza
2 month old vaccines
DTaP IPV HiB PCV Rotavirus
3 month old vaccines
DTaP MenC IPV HiB Rotavirus
4 month old vaccines
DTaP
PCV
IPV
HiB
12 month old vaccines
MMR
HiB/MenC
PCV
3 years and 4 months vaccines
MMR
IPV
DTaP
14 year old vaccines
Td
IPV
MenC
Bacteriostatic ABx
Tetracyclines (Doxycycline)
Sulphonamides
Trimethoprim
Vancomycin coverage
Gram +ve only
Gentamicin coverage
Gram -ve only
Vancomycin SEs
Red man syndrome
Nephrotoxic
Gentamicin SEs
Ototoxic (tinnitus, deafness, nystagmus)
Metronidazole coverage
Anaerobes
B lactam order of increasing spectrum
PBAFC To CCC ME Penicillin BenPen Amoxicillin Fluclox Co-amox Tazocin Cefuroxime Ceftriaxone Cefalexin Meropenem Ertapenem
Skin infection (S aureus) Abx
Fluclox
Pharyngitis (GAS) Abx
BenPen
CAP mild + severe Abx
Mild= Amox Severe= Cefuroxime + Clarithromycin
HAP Abx
Cefuroxime
Meningitis Abx
Ceftriaxone (BenPen in community)
Amox if Listeria likely
UTI Abx (community + hospital)
Community= Trimethoprim Nosocomial= Augmentin (Co-Amox)
Sepsis Abx (severe + neutropoenic)
Severe= Cefuroxime, Met + Gent Neutropoenic= Taz + Gent
C diff colitis Abx
Stop Ceph/Clinda/Cef
Metronidazole
TB meds SEs
R= Orange secretions, Hepatotox, cP45- inducer I= Peripheral neuropathy (B6 def), Hepatotox P= Hyperuricaemia, Hepatotox E= Optic neuritis, avoid in RF
CURB 65
Confusion (AMTS less than 8) Urea >7 RR >30 BP Less than 90/60 Age >65 3+ = hospital
Legionella pneumonia ABx
Macrolide + Rifampicin
S aureus pneumonia ABx
Fluclox
Pseudomonas pneumonia ABx
Taz
MRSA pneumonia ABx
Vanc
Aspiration pneumonia ABx
Cef + Met
Gonorrhoea Tx
IM Ceftriaxone 250mg or PO Cefotaxime 400mg
Chlamydia Tx
Azithromycin 1g PO or Doxycycline 100mg BD for 7/7
Syphilis Tx
IM BenPen
Trichomonas Tx
Met
Bacterial Meningitis CSF
Neuts, High Protein, Low Glucose
Viral Meningitis CSF
Lymphos, High Protein, Normal glucose
TB Meningitis CSF
Lymphos, V High Protein, Low Glucose
Diagnostic test for Leptospira
Microscopic Agglutination test
Prion disease feats
Demented LAMB LMN signs Akinetic mutism Myoclonus Blindness (Cortical)
(s)CJD CSF
Protein 14-3-3
EBV serology
+ve Paul Bunnell test
Atypical Lymphocytes
Heterophile Abs
CMV serology
Owl’s eye inclusions on fibroblast culture
HBV Tx
PegIFNalpha2a, Lamivudine, Tenofivir
HCV Tx
PegIFNalpha2b, Ribavarin