Micro Flashcards
What are the main causes of viral meningitis?
Enteroviruses
Main causes of viral encephalitis?
HSV1 and HSV2, rabies
Rabies- neuroinvasiveness and neurovirulence
BOTH neuroinvasive and neurovirulent
Is growth in cells an obligatory part of rabies virus life cycle?
Yes
HSV and VZV- neuroinvasiveness and neurovirulence
LOW neuroinvasive but HIGHLY neurovirulent
Is growth in cells an obligatory part of HSV life cycle?
Yes
Is growth in cells an obligatory part of polio virus life cycle?
No
Polio- neuroinvasiveness and neurovirulence
LOW neuroinvasive but HIGHLY neurovirulent
What are the 3 most common causes of bacterial meningitis in adults?
1) Hib
2) Strep pneumoniae
3) Nisseria meningitidis
What is common to the the 3 most common causes of bacterial meningitis?
They are all encapsulated- helps evade immune system and avoid phagocytosis and complement activation
What are the 3 most common causes of neonatal bacterial meningitis?
1) Listeria
2) Group B strep
3) E.Coli
What is the treatment for the the 3 most common causes of bacterial meningitis?
3rd generation cephalosporin
What about AB therapy for bacterial meningitis in neonates?
1) 3rd gen cephalosporin
2) Penicillin
3) Gentamicin