Michaelis-Menten Theory Flashcards
1
Q
What is the Michaelis-Menten kinetic theory of enzyme action?
A
An equation that relates the rate of an enzyme catalyzed reaction to substrate concentration and a ratio of rate of constants.
2
Q
How is the equation represented?
A
V = Vmax [S] / Km + [S]
3
Q
What does Vmax represent?
A
The rate when the enzyme is fully saturated with the substrate. [The maximum rate of reaction].
4
Q
What does V represent?
A
The rate or velocity of the reaction.
5
Q
What does Km represent?
A
[Michaelis constant] is the substrate concentration at which the rate of reaction os half the maximum velocity.
6
Q
What is the importance of Km?
A
- A constant for a particular enzyme under standardized conditions.
- Denotes enzyme affinity for its substrate.
- Permits evaluation of inhibitor type.
