(MHD) Lecture 7- Acute Kidney Injury

Question 1

What values for the following tests help you to determine whether the patient has Prerenal Azotemia or ATN?

1. Urinalysis
2. Urine Specific Gravity
3. Urine Osmolality
4. Urine Sodium
5. Fractional Excretion of Sodium
6. Fractional Excretion of Urea

Answer 1

Question 2

What is AIN? What causes it and what happens?

Answer 2

Acute Interstitial Nephritis

Drug Induced

“A” (Aristolochic acid = chinese therapy)

^ “I” (IgE/T cell mediated)

“N” (NSAIDs)

Drugs serve as haptons, making interstitium immunogenic

Question 3

Reasons for Dialyisis (5)

Answer 3

(A.E.I.O.U.)

Severe Cases of:

1. Acidosis
2. Electrolyte Derangment
3. Intoxication Syndrome
4. Overload (Pulmonary Edema)
5. Uremia