Methods of dating a pregnancy and maternal adaptations Flashcards

1
Q

Why is accurate dating of a pregnancy important?

A

Monitor the normal progress of pregnancy (both for mum & baby)
Educate mum / reassure / expectations
Early detection of problems in mum or baby / intervention
Prepare mum / family / health care team
Know if pregnancy is too short / possible prematurity
Know if pregnancy is too long / post dates

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2
Q

How long do the three trimesters last?

A

1st: 1-12 weeks
2nd: 13-28 weeks
3rd: 29-40 weeks

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3
Q

What is term, preterm and post term in pregnancy?

A

Term: 37-42 weeks
Preterm: 24-37 weeks
Post-term: 42+ weeks

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4
Q

What are the 3 major ways of dating a pregnancy?

A

1) Naegele’s Rule.. assumes a 28 day cycle and uses first day of last menstrual period (LMP)
2) Early ultrasound scan, crown rump length (CRL at 12 weeks)
3) Measuring of symphysio fundal height from 24 weeks

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5
Q

How does Naegele’s rule work?

A
Add 9 months 
Add 7 days to first day of LMP
(plus or minus days from resulting EDD for differing cycle length) e.g.
6 days for a 27 day cycle
7 days for a 28 day cycle
8 days  for a 29  cycle
9 days for a 30 day cycle
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6
Q

Sheeya comes to see you and she reports the following:
Regular 28 day cycle
LMP 7th September 2019
What is her EDD (Estimated delivery date)?

A

14th June 2020

add 9 months and 2 days

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7
Q

Kata comes to see you and she report the following:
35 day cycle
LMP 27th January 2020
What is her EDD?

A

10th Nov 2020

Add 9 months and 14 days

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8
Q

What happens at the 12 week scan that can change the EDD?

A

Crown-rump length (CRL)
(If above 84mm, gestational age should be estimated using head circumference)
if this differs more than 7 days from the Naegele’s rule then EDD will be adjusted

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9
Q

How do you measure the symphysio-fundal height? (SFH) hint: top down

A

Tape measure from top of fundus to top of symphysis of pubis

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10
Q

What maternal anatomical changes are there in pregnancy?

A
Mechanical effects as uterus enlarges
Bladder / Ureters (frequency of urine)
Gut (heartburn)
Diaphragm / Lungs
Heart / Aorta / Vena cava
Skin / Muscle (sweaty)
Lumbar spine
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11
Q

How do we check a pregnancy woman’s BP? What is the best position for her mum and baby?

A

Tilt woman on left side!

In the supine position - compression of aorta and IVC

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12
Q

What hormonal changes occur in pregnancy? What physiological changes occur in pregnancy?

A

First trimester: HCG - morning sickness
Second/Third trimester: Progesterone dominates/ oestrogen also high
Progesterone= Smooth muscle relaxant (varicosities, constipation)
Ureters-Dilated; Bladder-less tone
Gut-delayed peristalsis; full stomach
Decreased vascular resistance; fall in BP, dizziness, fainting
Skin-pigmentation.. Dark nipples; linea nigra
Human placental lactogen….glucose metabolism
Prolactin…preparing for lactation

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13
Q

How do levels of progesterone and oestrogen maintain the pregnancy?

A

Progesterone reduces muscle excitability by increasing ca binding thereby reducing free intracellular ca. Oestrogen increases myometrial excitability. It’s a fine balance.

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14
Q

What happens to oestrogen and progesterone levels at the onset of labour?

A

Near term, there is fall in progesterone level and an increase in oestrogen this induces myometrial excitability and stimulates prostaglandin synthesis and increased oxytocin receptors and the formation of gap junctions.

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15
Q

List the major changes in maternal physiology during a normal pregnancy

A
Cardiovascular System
Blood
Respiratory
Urinary / renal
Glucose Metabolism
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16
Q

What CVS adaptations occur during pregnancy?

A

Occur early- by 12-16 weeks
Heart enlarges a little due to increased workload; Apex displaced up and laterally (4th intercostal space)
Increased output (CO) from roughly 5 to 7ltrs per. min (more in labour)
Heart rate increases 10-15bpm
Stroke Volume increase
Vascular resistance falls
MAP falls by about 10mmHg; rises to normal as term approaches
Antenatal check: Hx of CVS disease / BP

17
Q

What blood adaptations occur during pregnancy?

A

Plasma Volume expands from 10th week ↑45%
Red cell mass (total volume of all RBCs) by ↑ 15%
Look at ratio - HAEMODILUTION
Therefore Hb, haematocrit and RBC all fall
Physiological anaemia by 28-34 weeks (haemodilution)
Circulating blood volume ↑50% by term
Toleration of blood loss is increased…birth
Many coagulation changes… generally pregnancy is PRO-THROMBOTIC (clotting time decreases)
Antenatal Check: Nutrition/Exercise/Iron/anaemia / regular blood tests/ advice / travel/ Hx of thrombosis

18
Q

What is the average blood loss at birth?

A

250 ml with vaginal delivery (more C/S)
Maternal adaptation allows toleration of haemorrhage better before showing a drop in BP
>500mls = post partum haemorrhage

19
Q

What respiratory adaptations occur during pregnancy?

A

Diaphragm pushed up - ribs flare to compensate
Increased alveolar exchange
Increased tidal volume
Slight drop in pCO2 ( to approx. 32 mmHg or 4.3 kPa)
↑ mucosal engorgement due to plasma volume expansion
nasal – epistaxis
Increased respiratory rate / maternal awareness/ dyspnoea/ mild respiratory alkalosis
Antenatal Check: Hx of respiratory disease / smoking

20
Q

By how much does O2 consumption increase in pregnancy and in stage 1 and stage 2 labour?

A

+35% ↑needs of foetus, uterus, placenta
+ 40% in stage I of labour
+ 75% in stage II of labour

21
Q

What urinary/renal system adaptations occur during pregnancy?

A

Increase in renal size
Changes in renin angiotensin system (Na balance)
Promote plasma expansion (Na + water retention)
Renal plasma flow and GFR are increased
Creatinine clearance is increased
Slightly lower absorption thresholds / glucose / protein
Increased risk of infection; dilated urethra and ureters /stasis
Antenatal Check: Hx of renal disease, urinalysis, BP, bloods, oedema

22
Q

What glucose metabolism adaptations occur during pregnancy?

A

Pregnancy is diabetogenic.
due to placental hormones (Placental lactogen, HGH, cortisol, progesterone).
Increased appetite/ fat deposition
Insulin resistance increases in pregnancy and levels rise
Post prandial glucose levels increase
Facilitates transfer to baby
Adaptive capacity of pancreatic insulin output may be overwhelmed……Gestational diabetes (GDM)
Antenatal Check: Risk assessment / nutrition and exercise/ screening for GDM

23
Q

What happens if adaptations in pregnancy don’t occur sufficiently?

A

Pre eclampsia

Gestational diabetes

24
Q

What is gestational diabetes?

A

Appears in roughly 4% of pregnancies.
Not enough insulin to counteract the “diabetogenic hormones” which increase in pregnancy
obesity also increasing in the population
tends to recur in future pregnancies
increases risk for type 2 DM later in life
increases risk to baby of macrosomia

25
Q

What are the risk factors of pre-eclampsia?

A
nulliparity - never having given birth
40 years or older 
pregnancy interval of more than 10years
Personal or  family history of pre‑eclampsia 
body mass index30kg/m2or above
pre‑existing renal disease
multiple pregnancies
26
Q

What are the 3 CRUCIAL clinical signs of pre-eclampsia? hint: BPO

A
1) High blood pressure
Failure of reduced vascular resistance
Failure of renal adaptation to pregnancy
2) Proteinuria
Leaking of glomeruli
3) Oedema
Leaking of capillaries with increased volume
27
Q

Outline why and how antenatal care monitors normal pregnancy adaptations

A

Early visits: Establish partnership care
Check medical and OB history
Agree anticipated due date
Discuss and arrange screening and pattern of care
Discuss ICE and lifestyle
Later visits: Monitor maternal adaptations / changes
Monitor foetal growth & development
Educate / advise / prepare