Methanol

Question 1

What is the methanol metabolism?

Answer 1

Question 2

Symptoms of methanol intoxication over time?

Answer 2

• Asymptomatic latency period
  
  • If ingested with ethanol ==> symptoms of ethanol intoxication
• Symptoms 8-30h later
  
  • ​Metabolic acidosis ==> respiratory failure
  • Abdominal pain (pancreatic damage)
  • Blindness (destructive inflammation ==> atrophy)

Question 3

Therapy methanol intoxication?

Answer 3

• Ethanol (10g/h)
• Fomepizole
• Hemodialysis