Metformin Flashcards

1
Q

Class of metformin

A

Biguanides

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2
Q

What enzyme does metformin target

A

AMP-kinase

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3
Q

How does metformin lower blood glucose

A

+ peripheral tissues sensitivity to insulin
— gluconeogenesis in liver
+ glucose uptake in target tissues

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4
Q

Indication for metformin

A

T2D (overweight)

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5
Q

Contraindication of metformin

A

Ketoacidosis

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6
Q

Side effect of metformin

A

Lactic acidosis

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