Metformin Flashcards
1
Q
Class of metformin
A
Biguanides
2
Q
What enzyme does metformin target
A
AMP-kinase
3
Q
How does metformin lower blood glucose
A
+ peripheral tissues sensitivity to insulin
— gluconeogenesis in liver
+ glucose uptake in target tissues
4
Q
Indication for metformin
A
T2D (overweight)
5
Q
Contraindication of metformin
A
Ketoacidosis
6
Q
Side effect of metformin
A
Lactic acidosis