Gliclazide Flashcards
1
Q
Class of gliclazide
A
Sulphonylureas
2
Q
What receptor does gliclazide block and what does that lead to
A
- ATP-sensitive K+ receptors
- — K efflux + depolarisation
- Ca entry & ++ insulin
3
Q
Indications for gliclazide
A
T2DM
4
Q
Contraindications for gliclazide
A
- ketoacidosis
- hepatic impairment
- pregnancy & b feeding
5
Q
Side effects of gliclazide
A
- hypoglycaemia
- hyponatraemia
- hepatotoxicity
6
Q
Gliclazide is mostly excreted via
A
Faeces
