Alendronate Flashcards
1
Q
Class of alendronate
A
Bisphosphonates
2
Q
Mechanism of bisphosphonates
A
++ osteoblast activity
— osteoclast activity
3
Q
Effect of bisphosphonates
A
— bone mass reduction
4
Q
Indications for bisphosphonates
A
- osteoporosis
- hypercalcaemia
- paget’s disease
- osteolytic lesions
5
Q
Contraindications of bisphosphonates
A
- pregnancy
- hypocalcaemia
- oesophageal abnormalities
6
Q
Side effects of bisphosphonates
A
- osteonecrosis
- oesophagitis
7
Q
Meds that — bisphosphonates absorption
A
- antacids
- oral iron
8
Q
Abx that ++ hypoglycaemia
A
Aminoglycosides
9
Q
How to take bisphosphonates
A
Empty stomach; sit straight for 30 mins
