Metastatic disease Flashcards

1
Q

Investigations for metastatic disease of unknown primary

A

FBC, U&Es, LFT, calcium, urinalysis, LDH

Chest xray

CT CAP

AFP and hCG

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2
Q

Specific investigations

A

Bone lesions- myeloma screen

Endoscopy

PSA

Women with peritoneal malignancy or ascites- CA 125

Men with germ cell tumours- testicular US

Mammography

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3
Q

Most common causes of bone metastases

A

Prostate

Breast

Lung

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4
Q

Most common sites for bone mets

A

Spine

Pelvis

Ribs

Skull

Long bones

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5
Q

Lung metastases from

A

Breast

Colon

Renal cell

Bladder

Prostate

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6
Q

Cannonball metastases

A

Round, well-defined lung secondaries (cannonball)

Most commonly seen with renal cell cancer (also choriocarcinoma, prostate cancer)

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