Metabolism (52-78) Flashcards

1
Q

Lipoprotein lipase

A

an enzyme in the capillary wall that catalyzed cleavage of fatty acids from lipids in lipoproteins (LDL, VLDL, etc.)

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2
Q

Polyuria

A

The excretion of an abnormally large quantity of urine

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3
Q

Polydipsia

A

Excessive thirst and water consumption

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4
Q

Ketoacidosis

A

Acidosis caused by the increased production of acidic ketone bodies (e.g. in diabetes mellitus)

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5
Q

Direct calorimetry

A

A measurement of heat actually produced by an organism confined in a sealed chamber or calorimeter

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6
Q

Indirect calorimetry

A

An estimation if the heat produced by an organism by measuring oxygen consumption and respiratory differences of oxygen and carbon dioxide in the inspired and expired air.

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7
Q

Incretins

A

Intestinal hormones increasing insulin secretion

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8
Q

Endogenous hyperglycemia

A

When the blood sugar level is abnormally high without carbohydrate consumption

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9
Q

Exogenous hyperglycemia

A

When the blood sugar level increases abnormal following carbohydrate consumption

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10
Q

Anabolism

A

A part of the intermediary metabolism, the syntheses of materials, building up the organisms own materials.

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11
Q

Catabolism

A

A part of the intermediary metabolism, the breaking down the absorbed compounds (usually from producing or storing energy).

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12
Q

Citric-acid cycle

A

(Szentgyörgyi-Krebs cycle)- The final breakdown of the two-carbonic compound acetyl-group that comes from either the glycolysis or the fatty-acid metabolism (beta-oxidation). The end-products are carbon dioxide and reduced co-enzymes.

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13
Q

Cori-cycle

A

A procedure in which the lactic-acid produced in the muscles under anaerobic conditions is re-metabolized to sugar in the liver on the expense of the break-down of its 1/3 amount.

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14
Q

Diabetes mellitus

A

A disease that occurs due to the ineffectiveness or lack of the insulin hormone. Symptoms are sugar in the urine, excess urination and over-drinking, acetone in the saliva, metabolic disturbances.

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15
Q

Pentose-phosphate cycle

A

An alternative route to the glycolysis in which 5 C-atom sugars and NADPH are formed

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16
Q

Fatty-acid synthesis

A

An enzymatic production of long-chained fatty-acids from acetyl co-enzyme-A (requires NADPH: a coenzyme)

17
Q

Glucogenic amino acids

A

Amino acids that can enter into the sugar metabolic pathways

18
Q

Gluconeogenesis

A

A procedure in which the liver synthesized de novo sugars from lactic acid and amino-acids (mainly from blood proteins)

19
Q

Glucolysis

A

A break-down procedure of 6-C sugars into acetyl (coenzyme A) group.

20
Q

Hyperglycemia

A

Elevated blood-sugar level

21
Q

Hypoglycemia

A

Decreased blood-sugar level.

22
Q

Ketogenic amino-acids

A

Amino-acids with ketone.like derivatives that cannot enter into the sugar metabolism.

23
Q

NAD (and NADH)

A

Co-enzyme that binds hydrogen in the glycolysis and in the citric-acid cycle, and that carries it to the oxidative phosphorylation.

24
Q

Lagerhans´islets

A

Hormone producing (endocrine) cell-groups of the pancreas

25
Q

Lipolysis

A

The breaking down of neutral fats into fatty-acids and glycerol.

26
Q

Oxidative phosphorilation

A

Final phase of the energy metabolism in the mitochondrion: hydrogen is moved from reduced co-enzymes to oxygen forming water, while released energy is stored in the form og ATP.

27
Q

Respiratory quotient

A

The carbon dioxide output divided by the oxygen uptake.