Metabolism Flashcards

0
Q

Exergonic

Endergonic

A

Reactions where more energy is released than used

Reactions where more energy is used than released

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1
Q

Anabolic

Catabolic

A
  • reductive pathway and uses intermediate metabolites and energy (ATP) to drive synthesis of important cell components
  • oxidative pathway releasing lots of free energy and produces intermediate metabolites
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2
Q

What is daily expenditure and what are the components

A

12000kJ and 9500kJ

BMR
Voluntary physical activity
Process food - diet induced thermogen

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3
Q

Fats are important in the diet

A

Yield 2.2 times more energy than carbs

Needed for absorption of lipid-soluble vitamins (ADEK)

Some polyunsaturated fatty acids (essential fatty acids) are regulators

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4
Q

Amino acids

A

Busing blocks of protein

Used in synthesis of essential N compounds - creatine, purines, pyrimidines, heam

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5
Q

BMI

A

Weight/height2

18-25 Normal
25-30 overweight
30-35 obese
>35 morbidly obese

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6
Q

Malnutrition

  • malabsorption
  • types of protein malnutrition
A

An in balance of consumption and expenditure

Malabsorption - coeliac and crohns

Protein deficient - marasmus and kwashiorkor

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7
Q

Marasmus

Kwashiorkor

A

Commonly under 5. Looks emaciated with obvious signs of loss in muscle and body fat, with no oedema. Hair is thin and dry. Diarrhoea and anaemia present

Normally young child with carb and very low protein diet. Child is apathetic, lethargic, anorexic. Generalised oedema and distended abdomen due to hepatomegaly. Low serum albumin and anaemia

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8
Q

Define homeostasis

A

The controlling of a dynamic equilibrium own internal environments.

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9
Q

Name cell nutrients

A
Glucose 
Amino acids 
Trigs
Cholesterol 
Fatty acids
Lactic acid 
Total CO2 
Urea
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10
Q

Why do cells metabolise nutrients

A

Energy for cell function - ATP
Building blocks molecules, synthesis for growth, repair and division
Organic precursor molecules that are used to allow interconversion of building block molecules (acetyl~CoA)
Biosynthetic reducing power used in synthesis of cell components (NADPH)

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11
Q

Where do cell nutrients in the blood come from?

A

Diet
Synthesis in body tissues from precursors
Released from storage in body tissues

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12
Q

What are th evasions chemical transformations that occur to circulating cell nutrients

A

Degradation - release energy in all cells
Synthesis of components - all tissues except mature erythrocytes
Storage - liver, adipose and skeletal muscle
Interconversion - liver, adipose, kidney cortex
Excretion - liver, kidney and lungs

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13
Q

Oxidation and reduction

A

Oxidation - addition of O2 and removal of H atom or electron

Reduction - removal of O2 and addition of H atom or electron

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