Lipid Transport, Byproducts Of Energy Flashcards

1
Q

Classes of lipoproteins

A

Chylomicrons
VLDL
LDL
HDL

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2
Q

What is a chyolomicron

A
Formed by enterocytes lining the
intestine
• Combine triacylglycerols fromfood with specific apoproteins
• Carry lipids from diet to tissues –
especially adipose tissue
• Normally only present in blood
4 – 6 h after a meal
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3
Q

What is a VLDL

A

Formed in liver for storage of energy
• Rich in triacylglycerols
• Combine triacylglycerols synthesised in liver with specific apoproteins
• Carry lipid from liver to tissues – mainlyadipose tissue

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4
Q

What is LDL

A

Formed in liver
• Cholesterol rich
• Combine cholesterol synthesised in liver withspecific apoproteins (Apo B100 is important)
• Carry cholesterol to tissues from liver
Increased = increased Risk of atherosclerosis

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5
Q

What is HDL

A

• Formed in tissues
• Cholesterol from tissues combined with
specific apoproteins
• Carry excess cholesterol back fromtissues toliver

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6
Q

What are the classes of hyperlipoproteinaemia

A

Type I - defect in lipoprotein lipase so chyolomicrons persist
Type II (a and b) A - high ldl (defect receptor) b high VLDL and LDL
Type III
Type IV
Type V

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7
Q

What are the classes of lipids

A
Trigs
Fatty acids
Cholesterol 
Cholesterol esters 
Phospholipids
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